Evidence map›Paper›PMID 40105878›Full record

ReviewEuropean heart journal2025

Leadless pacing: a comprehensive review.

Shmaila Saleem-Talib, Crispijn P R Hoevenaars, Nadine Molitor, Vincent J van Driel, Jeroen van der Heijden, Alexander Breitenstein, Harry van Wessel, Mathijs S van Schie, Natasja M S de Groot, Hemanth Ramanna

Abstract readReview
In one paragraph

Review in European heart journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Effective and potentially retrievable: will leadless pacemakers become gold standard for pause prevention pacing?European heart journal supplements : journal of the European Society of Cardiology · 2026
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  20. [Leadless cardiac pacemaker : Overview, tips, and tricks].Herzschrittmachertherapie & Elektrophysiologie · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shmaila Saleem-TalibDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands.ORCID 0000-0001-5053-3284
Crispijn P R HoevenaarsDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands.
Nadine MolitorElectrophysiology, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland.
Vincent J van DrielDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands.
Jeroen van der HeijdenDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands.
Alexander BreitensteinElectrophysiology, Department of Cardiology, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-4440-2947
Harry van WesselDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands.
Mathijs S van SchieDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Natasja M S de GrootDepartment of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Hemanth RamannaDepartment of Cardiology, Haga Teaching Hospital, The Hague, The Netherlands.ORCID 0009-0004-0441-0506

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade, leadless pacing has undergone a rapid evolution, resulting in multiple leadless pacemaker (LPM) devices that offer advancements such as atrioventricular synchronized pacing in VDD mode, atrial stimulation, dual-chamber pacing, and longer battery longevity. Studies comparing LPMs with transvenous pacemakers (TVPMs) show a lower rate of device-related complications with LPMs. In the near future, LPMs could be combined with other devices such as non-transvenous implantable cardioverter-defibrillators to provide anti-tachycardia pacing or bradycardia pacing. Future prospectives for leadless cardiac resynchronization therapy and leadless conduction system pacing are being investigated. As LPMs continue to improve, their applications are anticipated to expand further improving patient outcome, promising a bright future for leadless pacing. In this review, the past, present, and future of leadless pacing are discussed with a focus on cutting-edge implantation techniques, clinical outcomes, and modern advancements of LPMs.

Indexed as

Arrhythmias, CardiacCardiac Pacing, ArtificialPacemaker, ArtificialCardiac Resynchronization TherapyEquipment DesignForecastingHumansAVEIRCRTCSPLeadless pacemakerMicra

Identifiers

PMID40105878
PMCPMC12127730

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.