Evidence map›Paper›PMID 40105865›Full record

ArticleAging2025

Epigenetic and accelerated age in captive olive baboons (

Sarah J Neal, Shannon Whitney, Soojin V Yi, Joe H Simmons

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Longitudinal Baboon (Veterinary sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah J NealThe University of Texas MD Anderson Cancer Center, Michale E. Keeling Center for Comparative Medicine and Research, National Center for Chimpanzee Care, TX 78602, USA.
Shannon WhitneyTexas State University, Department of Biology Supple Science Building, TX 78666, USA.
Soojin V YiDepartment of Ecology and Evolution and Marine Biology, Department of Molecular, Cellular and Developmental Biology, Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA.
Joe H SimmonsThe University of Texas MD Anderson Cancer Center, Michale E. Keeling Center for Comparative Medicine and Research, National Center for Chimpanzee Care, TX 78602, USA.

Funding

Specific Pathogen Free Baboon Research Resource (SPFBRR) - Bridge Funding Administrative SupplementP40OD024628 · OD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI WILLIAM D HOPKINS · 2017 to 2026
$15.7M
NIH HHS P40 OD024628NSF
6 · The paper itself

Abstract

Epigenetic age, estimated by DNA methylation across the genome, reflects biological age. Accelerated age (i.e., an older methylation age than expected given chronological age) is an accepted aging biomarker in humans, showing robust associations with deleterious health outcomes, longevity, and mortality. However, data regarding age acceleration in nonhuman primates (NHPs), and relationships between NHP epigenetic age and behavioral indicators of aging, such as walking speed and fine motor performance, are sparse. We measured DNA methylation of 140 captive olive baboons (

Indexed as

AgingEpigenesis, GeneticPapio anubisWalking SpeedAnimalsDNA MethylationFemaleMaleaccelerating agingbaboonsbehavioral indicatorsDNA methylationepigenetics

Identifiers

PMID40105865
PMCPMC11984432

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.