Evidence map›Paper›PMID 40105600›Full record

SynthesisActa cirurgica brasileira2025

Performance of blood concentrates in controlling inflammatory signs and symptoms after lower third molar extractions: an overview.

Vinícius Lima de Almeida, Marcelo Dias Moreira de Assis Costa, Caio Melo Mesquita, Walbert Andrade Vieira, Rafael Rodrigues Lima, Livia Bonjardim Lima, Sigmar de Mello Rode, Luiz Renato Paranhos

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Acta cirurgica brasileira, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vinícius Lima de AlmeidaUniversidade Federal de Uberlândia - School of Dentistry - Post-Graduation Program in Dentistry - Uberlândia (MG) - Brazil.ORCID http://orcid.org/0000-0002-2135-1040
Marcelo Dias Moreira de Assis CostaUniversidade Federal de Minas Gerais - School of Dentistry - Department of Clinics, Pathology, and Oral Surgery - Belo Horizonte (MG) - Brazil.ORCID http://orcid.org/0000-0001-9148-3674
Caio Melo MesquitaUniversidade Federal de Uberlândia - School of Medicine - Multiprofessional Health Residency Program in Critical Patient Care - Uberlândia (MG) - Brazil.ORCID http://orcid.org/0000-0002-6892-3659
Walbert Andrade VieiraCentro Universitário das Faculdades Associadas de Ensino - Department of Dentistry - São João da Boa Vista (SP) - Brazil.ORCID http://orcid.org/0000-0001-8872-2865
Rafael Rodrigues LimaUniversidade Federal do Pará - Institute of Biological Sciences - Laboratory of Functional and Structural Biology - Belém (PA) - Brazil.ORCID http://orcid.org/0000-0003-1486-4013
Livia Bonjardim LimaUniversidade Federal de Uberlândia - School of Dentistry, Department of Oral and Maxillofacial Surgery and Traumatology - Uberlândia (MG) - Brazil.ORCID http://orcid.org/0000-0002-9924-4077
Sigmar de Mello RodeUniversidade Estadual Paulista - Institute of Science and Technology - Department of Dental Materials and Prothesis - São José dos Campos (SP) - Brazil.ORCID http://orcid.org/0000-0002-4261-4217
Luiz Renato ParanhosUniversidade Federal de Uberlândia - School of Dentistry - Department of Preventive and Community Dentistry - Uberlândia (MG) - Brazil.ORCID http://orcid.org/0000-0002-7599-0120

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo summarize the available evidence and answer the following question: What is the current knowledge on the performance of blood concentrates in handling sequelae after lower third molar extractions with the evidence available in systematic reviews?

methodsAn electronic search was conducted across nine databases. The study included systematic reviews with or without meta-analyses investigating the performance of blood concentrates in managing sequelae after lower third molar extractions. The four outcomes analyzed were pain, edema, mouth opening, and alveolar osteitis. The AMSTAR-2 tool assessed the methodological quality of the included systematic reviews, while ROBIS evaluated the risk of bias.

resultsThe electronic search revealed 690 records, of which 15 were eligible systematic reviews for the present study. Overall, these reviews evaluated 75 primary studies published from 2007 to 2023. According to AMSTAR-2, only one systematic review presented high methodological quality. The ROBIS tool showed two systematic reviews with a low risk, and the others had a high risk of bias.

conclusionThe current evidence is based on only one systematic review with high methodological quality and a low risk of bias, while the others exhibited a high risk of bias and low methodological quality. Therefore, the evidence regarding the efficacy of blood concentrates in controlling sequelae following lower third molar extractions is inconclusive.

Indexed as

Dry SocketMolar, ThirdPostoperative ComplicationsTooth ExtractionEdemaHumansSystematic Reviews as TopicTreatment Outcome

Identifiers

PMID40105600
PMCPMC11908738

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.