Evidence map›Paper›PMID 40105569›Full record

ArticleEinstein (Sao Paulo, Brazil)2025

Aortic calcium score predicts early outcomes in aortoiliac revascularization.

Adalberto Batalha Megale, Nelson Wolosker, Vitoria Magliari Kalil, João Mário Nigro, Carolina Sciammarella Wakisaka, Bianca Oberhuber Dias, Marcelo Passos Teivelis, Marcelo Assis Rocha, Cynthia de Almeida Mendes

Abstract read
In one paragraph

Article in Einstein (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adalberto Batalha MegaleHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-6943-5569
Nelson WoloskerHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0003-1991-3507
Vitoria Magliari KalilHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0007-3450-015X
João Mário NigroHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0005-5744-6067
Carolina Sciammarella WakisakaHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0008-9426-5638
Bianca Oberhuber DiasHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0003-6938-3951
Marcelo Passos TeivelisHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-3648-6773
Marcelo Assis RochaHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-0312-4821
Cynthia de Almeida MendesHospital Israelita Albert Einstein, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-9266-8144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCalcium scores were evaluated in the lower limbs of patients with clinical limb ischemia after aortoiliac revascularization. The aortic calcium score was related to the short-term outcomes of amputation and subsequent revascularization. Similarly, the calcium score in below-the-knee arteries was associated with revascularization and amputation at 12 months. ■ The calcium score can be calculated using computed tomography angiography. ■ The aortic calcium score was associated with amputation and subsequent revascularization within 30 days. ■ The calcium score in below-the-knee arteries was higher in the patients who underwent subsequent revascularization and amputation at 12 months.

objectiveTo evaluate the association between lower limb artery calcium scores in preoperative computed tomography angiography and outcomes of patients with critical limb ischemia who underwent revascularization procedures in the aortoiliac segment.

methodsWe retrospectively reviewed 14 interventions performed on 11 patients. The calcium score was calculated in segments of the aorta, iliac, femoropopliteal, and below-the-knee arteries. The evaluated outcomes included amputation, patency, death, subsequent revascularization, and readmission. Major adverse limb events were defined as amputation, subsequent revascularization, or readmission. The patients were followed through a 12-month period.

resultsHigher aortic calcium scores were associated with amputation within 30 days (5,767.6 versus 805.3; p=0.02). Amputation during the first year correlated with a higher below-the-knee arteries calcium score (672.4 versus 163.25; p=0.04). Subsequent revascularization within 30 days was associated with a higher aortic calcium score (3,686.8 versus 645.2; p=0.008), while below-the-knee arteries calcium scores were associated with revascularization within 30 days (155.5 versus 817; p=0.05) and 12 months (158.875 versus 679.4; p=0.019). Readmissions within 1 year were more prevalent with higher below-the-knee arteries calcium scores (882.4 versus 32; p=0.011). Major adverse limb events were related to below-the-knee arteries calcium scores at 30 days (158.875 versus 679.4; p=0.019) and 1 year (12.3 versus 910.1; p=0.002).

conclusionBelow-the-knee arteries calcium score is a predictor of long-term revascularization, amputation, readmission, and major adverse limb events. The aortic calcium score was associated with amputation and subsequent revascularization within the first 30 days.

Indexed as

Iliac ArteryIschemiaLower ExtremityVascular CalcificationAgedAmputation, SurgicalComputed Tomography AngiographyFemaleHumansMaleMiddle AgedPeripheral Arterial DiseaseRetrospective StudiesTime FactorsTreatment Outcome

Identifiers

PMID40105569
PMCPMC11908746

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.