ArticleRevista da Associacao Medica Brasileira (1992)2025
Pregnancy and delivery outcomes in coronavirus disease 2019: a cross-sectional study from a tertiary center.
Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Impacts of hypothyroidism on clinical, delivery, and fetal outcomes of coronavirus disease 2019: a cross-sectional study.Revista da Associacao Medica Brasileira (1992) · 2026Article
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5 authors.
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Abstract
objectiveThe objective of this study was to document the clinical and laboratory characteristics and maternal and delivery outcomes of pregnant women with coronavirus disease 2019.
methodsWe retrospectively assessed pregnant women who had been admitted either with symptoms of coronavirus disease 2019 or for delivery from March 2020 to January 2023. The participants were evaluated in two cohorts: the initial cohort included all pregnant women hospitalized with coronavirus disease 2019, and the final cohort included those who delivered under the circumstances of coronavirus disease 2019.
resultsThe initial cohort included 295 pregnant women with symptomless (n=124, 42%), mild (n=122, 41.4%), moderate (n=18, 6.1%), and severe (n=31, 10.5%) coronavirus disease 2019. Among comorbidities, hypothyroidism (n=40, 13.6%) had the highest share. The most frequent laboratory abnormality was elevated D-dimer levels (94.6%). The final cohort included 193 women. Eight patients (4.1%) required intensive care unit (ICU) stay. Mortality occurred in five patients (2.6%). Out of 121 cesarean section (SC) deliveries, 61.2% were on an emergency basis. Rates of preterm, low birth weight, and stillbirth were 18.7%, 14.5%, and 3.1%, respectively. Moderate-severe coronavirus disease 2019 showed significant inverse correlations with delivery week, birth weight, and APGAR scores at 1 and 5 min (p<0.0001).
conclusionA considerable proportion of pregnant women with coronavirus disease 2019 experienced maternal and delivery complications, particularly preterm and low birth weight. Hypothyroidism had a notable share among comorbidities.
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