ArticleBrazilian oral research2025
The impact of intracanal medicaments on crown color, pH, and antimicrobial activity: a comparative study.
Article in Brazilian oral research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of tricalcium silicate-based intracanal dressing on antibacterial-antifungal activity and postoperative pain intensity after non-surgical endodontic retreatment: randomized controlled clinical trial.Head & face medicine · 2025Trial
- Effect of Bio-C Temp calcium silicate-based intracanal medication on the chemical composition and fracture resistance of root dentin.Odontology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to compare the effects of intracanal medication pastes Bio-C Temp® (BC), UltraCal XS® (UC), and Pure Calcium Hydroxide (CH) on crown color change, pH, and antimicrobial activity. Color change was assessed using the CIEL*a*b* color space system parameter. pH values were measured at 3, 24, 72, and 168 hours. Antimicrobial activity was evaluated using agar diffusion and direct exposure tests. Statistical analyses were conducted using ANOVA, Kruskal-Wallis, and Friedman tests (α = 0.05). After 15 days, BC exhibited significantly greater color variation than the control, and higher L* values at 60 days compared to baseline (p < 0.05). BC demonstrated lower pH values than UC and CH at 3 and 72 hours (p < 0.05). In the agar diffusion test, BC produced a smaller microbial inhibition halo than UC and CH. In the direct exposure test, CH completely inhibited microbial growth, whereas BC showed microbial growth at all evaluated time points. In conclusion, BC resulted in greater crown color change, lower pH, and reduced antimicrobial activity compared to UC and CH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.