Evidence map›Paper›PMID 40105497›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Comparative Analysis of Information Quality in Pediatric Otorhinolaryngology: Clinicians, Residents, and Large Language Models.

Eleonora M C Trecca, Vito Carlo Alberto Caponio, Mario Turri-Zanoni, Antonella Miriam di Lullo, Michele Gaffuri, Jérôme R Lechien, Antonino Maniaci, Giuseppe Maruccio, Marella Reale, Irene Claudia Visconti and 1 more

Abstract readComparative Study
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Three-dimensional printing and cochlear implantation: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Review
  2. Article
  3. Predicting recovery in Bell's palsy: the impact of early rehabilitation and prognostic indicators.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Comparative diagnostic accuracy of ChatGPT models in salivary gland disease: a multimodal vignette-based evaluation.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eleonora M C TreccaGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0001-6490-1746
Vito Carlo Alberto CaponioDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.ORCID http://orcid.org/0000-0001-5080-5921
Mario Turri-ZanoniGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0002-3678-9088
Antonella Miriam di LulloGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID https://orcid.org/0000-0002-4482-6782
Michele GaffuriGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0002-5435-685X
Jérôme R LechienDepartment of Otolaryngology-Head and Neck Surgery, Division of Laryngology and Bronchoesophagology, Baudour, Belgium.ORCID http://orcid.org/0000-0002-0845-0845
Antonino ManiaciGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0002-1251-0185
Giuseppe MaruccioDepartment of Otolaryngology-Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy.ORCID https://orcid.org/0009-0008-6474-2122
Marella RealeGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0002-9716-8605
Irene Claudia ViscontiGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0002-5831-1042
Virginia DallariGOS, Young Otolaryngologists Group of the Italian Society of Otorhinolaryngology-Head and Neck Surgery, Rome, Italy.ORCID http://orcid.org/0000-0001-9260-1003

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePediatric otorhinolaryngology (ORL) addresses complex conditions in children, requiring a tailored approach for patients and families. With artificial intelligence (AI) gaining traction in medical applications, this study evaluates the quality of information provided by large language models (LLMs) in comparison to clinicians, identifying strengths and limitations in the field of pediatric ORL. STUDY

designComparative blinded study.

settingControlled research environment using LLMs.

methodsFifty-four items of increasing difficulty, namely 18 theoretical questions, 18 clinical scenarios, and 18 patient questions, were posed to ChatGPT-3.5, -4.0, -4o, Claude-3, Gemini, Perplexity, Copilot, a second-year resident, and an expert in the field of pediatric ORL. The Quality Analysis of Medical Artificial Intelligence (QAMAI) tool was used for blinded evaluation of the quality of medical information by a panel of expert members from the Young Otolaryngologists Group of the Italian Society of ORL and the International Federation of ORL Societies.

resultsLLMs performed comparably to specialist in theoretical and standardized clinical scenarios, with Bing Copilot achieving the highest QAMAI scores. However, AI responses lacked transparency in citing reliable sources and were less effective in addressing patient-centered questions. Poor interrater agreement among reviewers highlighted challenges in distinguishing human-generated from AI-generated responses. Rhinology topics received the highest scores, whereas laryngology and patient-centered questions showed lower agreement and performance.

conclusionLLMs show promise as supportive resources in pediatric ORL, particularly in theoretical learning and standardized cases. However, significant limitations remain, including source transparency and contextual communication in patient interactions. Human oversight is essential to mitigate risks. Future developments should focus on refining AI capabilities for evidence-based and empathetic communication to support both clinicians and families.

Indexed as

Artificial IntelligenceData AccuracyInternship and ResidencyLanguageOtolaryngologyPediatricsChildHumansLarge Language Modelsartificial intelligenceChatGPTdigital healtheHealthlarge language modelsotolaryngologypediatric otorhinolaryngologypediatrics

Identifiers

PMID40105497
PMCPMC12207379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.