Evidence map›Paper›PMID 40105480›Full record

Observational studyThe British journal of surgery2025

Development and external validation of prediction risk scores (STRISK and NOFA) to predict immediate surgical need in adhesive small bowel obstruction: an observational prospective multicentre study.

Panu Räty, Akseli Bonsdorff, Helka Parviainen, Eila Lantto, Thomas Hackenberg, Hanna Lampela, Taina Nykänen, Ilana Lyytinen, Panu Mentula, Ville Sallinen

Abstract readObservational StudyMulticenter StudyValidation Study
In one paragraph

Observational study in The British journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Clinical performance of the Antoine Béclère score in predicting operative requirement in adhesive small bowel obstruction.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Panu RätyGastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0001-6088-4547
Akseli BonsdorffGastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0002-2096-6131
Helka ParviainenHUS Medical Imaging Center, Radiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Eila LanttoHUS Medical Imaging Center, Radiology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Thomas HackenbergDepartment of Surgery, Hyvinkää Hospital, Hyvinkää, Finland.
Hanna LampelaGastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Taina NykänenDepartment of Surgery, Hyvinkää Hospital, Hyvinkää, Finland.
Ilana LyytinenDepartment of Surgery, Kanta-Häme Central Hospital, Hämeenlinna, Finland.
Panu MentulaGastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0002-6516-3797
Ville SallinenGastroenterological Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0001-5394-4169

Funding

Finnish Medical FoundationHelsinki University Hospital Research FundsMary and Georg Ehrnrooth's FoundationOrion Research FoundationVatsatautien Tutkimussäätiö Foundation
6 · The paper itself

Abstract

backgroundAdhesive small bowel obstruction (SBO) is a common cause of emergency admission. Identification of patients at high risk of strangulation or failure of non-operative treatment is difficult. In this multicentre prospective observational study, prediction models for strangulation and non-operative treatment failure in adhesive SBO were developed.

methodThis study was carried out in three Finnish hospitals between June 2014 to May 2022. Patients with CT-confirmed adhesive SBO and prospective case report forms were included. The main outcomes were strangulation defined by operative finding of any intestinal ischaemia and failure of non-operative treatment within 30 days from admission. The model was developed using binary logistic regression, internally validated by bootstrapping and then externally validated.

resultsOf 626 patients, 481 were included; 355 patients formed the model development group and 126 formed the external validation group. Strangulation occurred in 58 (16%) patients and non-operative treatment failed in 93 (31%) patients in development cohort. The following six variables were included in the risk model for strangulation and non-operative treatment failure: neutrophil-leucocyte ratio, number of previous SBOs, abdominal guarding, mesenteric changes and free abdominal fluid, closed loop sign, and faeces sign on CT. In the development cohort, the optimism corrected area under the receiver operator characteristics curve for the strangulation model was 0.860 (95% c.i. 0.808-0.917), and 0.751 (95% c.i. 0.694-0.816) for the non-operative treatment failure model respectively. At external validation, the models retained their discrimination and demonstrated stable calibration.

conclusionA clinically relevant prediction model to predict strangulation and non-operative treatment failure in adhesive small bowel obstruction has been developed.

Indexed as

Intestinal ObstructionIntestine, SmallAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesRisk AssessmentRisk FactorsTissue AdhesionsTreatment Failure

Identifiers

PMID40105480
PMCPMC11921420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.