Evidence map›Paper›PMID 40105448›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

Who Is Diagnosing Pediatric Thyroid Nodules? A Tertiary Children's Hospital Review.

Joy M Justice, Janavi Sethurathnam, Nanda Nayak, Heidi Chen, Kalpnaben Patel, Sara Bartz, Christopher Baron, Barron Patterson, Ryan H Belcher

Abstract read
In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Joy M JusticeVanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID http://orcid.org/0009-0001-8984-1249
Janavi SethurathnamVanderbilt University School of Medicine, Nashville, Tennessee, USA.
Nanda NayakVanderbilt University School of Medicine, Nashville, Tennessee, USA.
Heidi ChenVanderbilt University Department of Biostatistics, Nashville, Tennessee, USA.
Kalpnaben PatelSurgical Outcomes Center for Kids (SOCKS), Nashville, Tennessee, USA.
Sara BartzVanderbilt University Department of Pediatrics, Division of Pediatric Endocrinology and Diabetes, Nashville, Tennessee, USA.
Christopher BaronVanderbilt University Department of Radiology, Nashville, Tennessee, USA.
Barron PattersonVanderbilt University Department of Pediatrics, Nashville, Tennessee, USA.
Ryan H BelcherVanderbilt University Department of Otolaryngology-Head and Neck Surgery, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-9490-3694

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe incidence of pediatric thyroid cancer has increased. Little is documented about which providers are diagnosing pediatric thyroid nodules and how this impacts care. Our objective was to analyze how nodules are identified and how diagnosing provider type impacts nodule size and management. STUDY

designRetrospective chart review.

settingTertiary care children's hospital.

methodsPediatric patients (aged 0-17) with at least one thyroid nodule diagnosed between 2006 and 2023 were reviewed. Diagnosing provider type, diagnostic method, nodule size, clinical management, and final diagnosis were analyzed.

resultsThe study included 351 patients. Primary care providers diagnosed the largest proportion of nodules (43.0%), followed by incidental nodules by radiologists (24.2%). The proportion diagnosed by radiologists increased from 12% to 31% after 2017 (P < .001). Primary care providers were more likely to use physical exam than pediatric endocrinologists (65% vs 42%, P = .004), who more often used ultrasound (56% vs 37%, P = .02). Primary care providers diagnosed nodules with a median diameter of 1.50 cm, larger than that of pediatric endocrinologists and radiologists, both 0.8 cm (P = .01, P < .001). Compared to patients diagnosed by radiologists, patients diagnosed by primary care providers more often underwent biopsy (P = .02) or surgery (P < .001) and received a malignant diagnosis (P = .001).

conclusionPrimary care providers play a key role in detecting pediatric thyroid nodules, and a physical exam is vital in identifying significant pathology. Radiologic incidental nodules increased in frequency over our study timespan. Future research should consider the impact of socioeconomic status or geographic location on nodule size and management.

Indexed as

Thyroid NoduleAdolescentChildChild, PreschoolFemaleHospitals, PediatricHumansInfantInfant, NewbornMaleRetrospective StudiesTertiary Care CentersUltrasonographynodule sizepediatric thyroid noduleprimary care providers

Identifiers

PMID40105448
PMCPMC12207357

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.