Evidence map›Paper›PMID 40105332›Full record

ArticleMicrobiology resource announcements2025

Transcriptome of brain-like endothelial cells following coxsackievirus B3 infection.

Sarah F Hathcock, Taryn E Keyzer, Nadine Vollmuth, Daryl W Lam, Jon Sin, Brandon J Kim

Abstract read
In one paragraph

Article in Microbiology resource announcements, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sarah F Hathcock *Department of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.ORCID 0009-0002-6699-3263
Taryn E Keyzer *Department of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.ORCID 0009-0008-8185-4636
Nadine VollmuthDepartment of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.
Daryl W LamDepartment of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.
Jon SinDepartment of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.ORCID 0000-0002-2567-3223
Brandon J KimDepartment of Biological Sciences, University of Alabama, Tuscaloosa, Alabama, USA.ORCID 0000-0003-0476-8028

Funding

Targeting transient receptor potential channels to suppress proviral mitochondrial fission and mitophagy in order to mitigate CVB pancreatitisR01DK125692 · NIDDK · UNIVERSITY OF TEXAS DALLAS · PI SIN, JON · 2021 to 2025
$1.6M
Impairment of the cerebral vasculature during bacterial meningitisR15NS131921 · NINDS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI CORRELL, ROBERT NATHAN · 2023 to 2023
$447k
HHS | National Institutes of Health (NIH) R01DK125692HHS | National Institutes of Health (NIH) R15NS131921NIDDK NIH HHS R01 DK125692NINDS NIH HHS R15 NS131921
6 · The paper itself

Abstract

Coxsackievirus B3 is a leading cause of viral aseptic meningitis. To gain entry to the central nervous system, it must interact with and disrupt the brain endothelial cells of the blood-brain barrier. Here, we report the global transcriptome of stem-cell-derived brain-like endothelial cells during coxsackievirus B3 infection.

Indexed as

blood-brain barriercoxsackievirusRNAseqtranscriptome

Identifiers

PMID40105332
PMCPMC11984143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.