ReviewPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2025
Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.
Review in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- CRD-guided step-up care for pediatric dust mite allergy: A systematic review of evidence gaps and global disparities (2014-2025).The World Allergy Organization journal · 2026Review
- Aeroallergens in Atopic Dermatitis and Chronic Urticaria.Current allergy and asthma reports · 2026Review
- Article
- Polysensitization Patterns and Age-Dependent Allergen Profiles in Children from Suzhou, China: A Component-Resolved Cross-Sectional Study.Journal of asthma and allergy · 2026Article
- Editorial: Allergens and allergic sensitization in Asia and the tropics-volume II.Frontiers in allergy · 2026Article
- Immunoblotting Analysis of Fruit Proteins in Mexican Pediatric Patients Suggests the Existence of New Allergens.Diseases (Basel, Switzerland) · 2025Article
- The Allergy Crossroads of Subtropical Regions: Mites, Crustaceans, and the Rise of Edible Insects.Nutrients · 2025Article
- Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Review
- Proteomic and Allergenomic Profiling of Banana (Journal of asthma and allergy · 2025Article
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Authors and funding
9 authors.
Funding
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Abstract
Component-resolved diagnostics (CRD) have revolutionized allergy diagnosis, offering enhanced accuracy and insights into allergen sensitization patterns. This review explores geographical variances in CRD for food and aeroallergens across the Asia-Pacific region. We examine the varying prevalence of allergic diseases and the utility of CRD in diagnosing common food allergies, including peanut, shellfish, fish, wheat, and fruits. Notable differences in serum-specific (sp)IgE sensitization patterns and the clinical relevance of particular allergen components are observed between populations in Asian countries and those in Europe and the United States. For food allergies, the literature reports significant differences in allergen components and their diagnostic utility across various countries. Peanut allergy diagnostics, particularly Ara h 2 spIgE, show varying sensitivity and specificity between Asian and Western populations. In shellfish allergy, emerging allergens beyond tropomyosin are gaining importance in the Asia-Pacific region. Fish and wheat allergies also demonstrate unique sensitization patterns, emphasizing the need for region-specific diagnostic approaches. Regarding aeroallergens, pollen sensitization profiles vary widely across the region, influenced by local flora and climate, to influence symptoms of pollen food allergy syndrome. House dust mite allergens remain a significant concern, with high sensitization rates to major components like Der p 1, Der p 2, and the emerging Der p 23. The cross-reactivity between house dust mite and shellfish allergens is particularly relevant in this region. These findings emphasize the need for region-specific CRD approaches, considering local allergen profiles and sensitization patterns. As the prevalence of allergic diseases continues to rise in the Asia-Pacific, further research into locally relevant allergens and their components is crucial for improving diagnosis, patient management, and targeted immunotherapy strategies in this diverse region.
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