Evidence map›Paper›PMID 40105250›Full record

ArticleHeadache

Migraine and sleep apnea, insomnia, and sleep patterns in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL).

Angeliki Vgontzas, Murray A Mittleman, Cecilia Castro-Diehl, Carmen R Isasi, Richard B Lipton, Sanjay R Patel, Alberto Ramos, Daniela Sotres-Alvarez, Christian Agudelo, Martha L Daviglus and 3 more

Abstract read
In one paragraph

Article in Headache. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Sleep and Headache Disorders: What a Clinician Needs to Know.Current neurology and neuroscience reports · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Angeliki VgontzasDivision of Headache Medicine, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-5191-1475
Murray A MittlemanDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Cecilia Castro-DiehlDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA.
Richard B LiptonMontefiore Headache Center, Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0003-2652-2897
Sanjay R PatelDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Alberto RamosEvelyn F. McKnight Brain Institute, Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Daniela Sotres-AlvarezDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Christian AgudeloEvelyn F. McKnight Brain Institute, Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.
Martha L DaviglusInstitute for Minority Health Research, University of Illinois-Chicago, Chicago, Illinois, USA.
Phyllis C ZeeDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Susan RedlineDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Suzanne M BertischDivision of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Funding

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating CenterOT2HL156812 · NHLBI · RESEARCH TRIANGLE INSTITUTE · PI NOLEN, TRACY L, THOMAS, SONIA M · 2020 to 2024
$1270.7M
Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI CAROL A. DERBY · 1985 to 2026
$73.9M
Neuroimaging CoreU19AG076581 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI GABRIEL Alejandro DE ERAUSQUIN, Gabriela Gonzalez_Aleman · 2023 to 2026
$32.9M
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's diseaseR01AG075758 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Charles DeCarli, Hector M Gonzalez · 2022 to 2026
$21.7M
The Illinois Precision Medicine Consortium (IPMC) All of Us Research Program SiteOT2OD036445 · OD · UNIVERSITY OF CHICAGO · PI Habibul Ahsan, Briseis A Aschebrook-Kilfoy · 2023 to 2026
$20.3M
Integrated Care for Chronic Pain and Opioid Use Disorder: The IMPOWR Research Center at Montefiore/Einstein (IMPOWR-ME)RM1DA055437 · NIDA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI ARNSTEN, JULIA H., GABBAY, VILMA · 2021 to 2025
$13.7M
Sleep in Neurocognitive Aging and Alzheimers Research (SANAR)R01AG067568 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Alberto Rafael Ramos · 2021 to 2026
$13.7M
TRAINING GRANT IN SLEEP RESEARCHT32HL007909 · NHLBI · NORTHWESTERN UNIVERSITY · PI FRED W TUREK, Phyllis C. Zee · 1998 to 2026
$9.2M
Coronary Artery Calcium and its Association with Protective/Risk Factors and Epigenetic Patterns in Diverse US Hispanic/Latino AdultsR01HL152692 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BUDOFF, MATTHEW J, DAVIGLUS, MARTHA L · 2021 to 2024
$8.8M
Validation of the Remote Cognitive Aging and Alzheimer’s Disease REsearch (R-CARE) Toolbox for Diverse PopulationsR01AG080635 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Ali Ezzati, Richard B. LIPTON · 2023 to 2026
$8.6M
The influence of structural violence and individual behavior and health on the gut microbiome and colorectal cancer riskU54MD012523 · NIMHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WINN, ROBERT A. · 2017 to 2022
$7.9M
Randomized Control Trial of oxygen therapy in Children and Adolescents with Down Syndrome and Obstructive Sleep ApneaR61HL165366 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI AMIN, RAOUF S., REDLINE, SUSAN S. · 2022 to 2023
$7.3M
FDA HHS UG3 FD006795National Heart, Lung, and Blood Institute (NHLBI) HHSN268201300001I/N01-HC-65233National Heart, Lung, and Blood Institute (NHLBI) HHSN268201300002I/N01-HC-65235National Heart, Lung, and Blood Institute (NHLBI) HHSN268201300003I/N01HC-65236National Heart, Lung, and Blood Institute (NHLBI) HHSN268201300004I/N01-HC-65234National Heart, Lung, and Blood Institute (NHLBI) HHSN268201300005I/N01-HC-65237NCCIH NIH HHS R01 AT011005NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300001CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS HHSN268201300004CNHLBI NIH HHS HHSN268201300005CNHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS OT2 HL156812NHLBI NIH HHS R01 HL140580NHLBI NIH HHS R01 HL152692NHLBI NIH HHS R01 HL159647NHLBI NIH HHS R61 HL164688NHLBI NIH HHS R61 HL165366NHLBI NIH HHS T32 HL007909NIA NIH HHS L30 AG074434NIA NIH HHS P01 AG003949NIA NIH HHS R01 AG067568NIA NIH HHS R01 AG075758NIA NIH HHS R01 AG077639NIA NIH HHS R01 AG080635NIA NIH HHS RF1 AG057531NIA NIH HHS U19 AG076581NIDA NIH HHS RM1 DA055437NIH HHS OT2 OD036445NIMHD NIH HHS U54 MD012523NINDS NIH HHS K23 NS107643NINDS NIH HHS R01 NS123374NINDS NIH HHS R61 NS125153NINDS NIH HHS U24 NS113847
6 · The paper itself

Abstract

objectiveTo quantify the prevalence of migraine and examine its association with sleep disorders, patterns, and symptoms in adults in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). We hypothesized that migraine would be associated with insomnia but not sleep apnea.

backgroundSparse research has examined migraine prevalence and sleep comorbidities in underrepresented racial and ethnic groups in the United States. Hispanic/Latino adults in the United States may be at risk for worse health outcomes due to disparities in health-care access and socioeconomic stressors.

methodsWe analyzed data collected during the baseline examination (March 2008-June 2011) from the HCHS/SOL, a community-based cohort study of self-identified Hispanic/Latino adults in the United States. The exposure was self-reported medical diagnosis of migraine, and primary outcomes were obstructive sleep apnea (apnea-hypopnea index ≥ 15 events/h from at-home sleep testing) and insomnia (≥ 9 on the Women's Health Initiative Insomnia Rating Scale). Exploratory outcomes included self-reported sleep duration, timing, sleeping pill use, and naps. We compared weighted differences in outcomes by migraine status, adjusting for age and sex in all reported models.

resultsOur analytical sample included HCHS/SOL participants who completed questionnaires on sleep and migraine (16,325). The mean age (standard deviation) was 41.1 (31.7) years, 52.2% identified as female, and 39.5% had a body mass index ≥ 30 kg/m

conclusionSelf-reported medical diagnosis of migraine is common in Hispanic/Latino adults, especially females. Migraine is not associated with obstructive sleep apnea. Consistent with non-Hispanic/Latino populations, migraine is associated with insomnia in the HCHS/SOL.

Indexed as

Hispanic or LatinoMigraine DisordersSleep Apnea SyndromesSleep Initiation and Maintenance DisordersAdultAgedCohort StudiesComorbidityFemaleHumansMaleMiddle AgedPrevalenceUnited StatesHispanic/Latinohome sleep studyinsomniamigrainesleep apnea

Identifiers

PMID40105250
PMCPMC12353483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.