Evidence map›Paper›PMID 40105050›Full record

ArticlePalliative medicine2025

Systematic adaptation of public health palliative care interventions across settings using ADAPT guidance: Methodological learnings from the EU NAVIGATE project.

Fien Van Campe, Kenneth Chambaere, Lara Pivodic, Joni Gilissen, Barb Pesut, Wendy Duggleby, Tinne Smets, Katarzyna Szczerbińska, Maja Furlan de Brito, Andrew Davies and 5 more

Abstract read
In one paragraph

Article in Palliative medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Fien Van CampeEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Universiteit Gent, Brussels, Belgium.ORCID 0000-0002-0742-7475
Kenneth ChambaereEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Universiteit Gent, Brussels, Belgium.ORCID 0000-0001-6277-072X
Lara PivodicEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Universiteit Gent, Brussels, Belgium.ORCID 0000-0002-8825-3699
Joni GilissenEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Universiteit Gent, Brussels, Belgium.
Barb PesutUniversity of British Columbia Okanagan, Kelowna, BC, Canada.
Wendy DugglebyFaculty of Nursing, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0002-3444-0392
Tinne SmetsEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Universiteit Gent, Brussels, Belgium.ORCID 0000-0003-1439-316X
Katarzyna SzczerbińskaLaboratory for Research on Aging Society, Chair of Epidemiology and Preventive Medicine, Medical Faculty, Jagiellonian University Medical College, Krakow, Poland.ORCID 0000-0002-0004-3858
Maja Furlan de BritoFaculty of Medicine, University of Coimbra, Coimbra, Portugal.ORCID 0000-0002-3749-7183
Andrew DaviesTrinity College Dublin, Dublin, Ireland.
Davide FerrarisLega Italiana per la lotta contro i tumori di Milano, LILT Milano Monza Brianza, Milano, Italy.
Annicka van der PlasAmsterdam UMC, Vrije Universiteit Amsterdam, Department of Public and Occupational Health, Expertise Center for Palliative Care Amsterdam UMC, Amsterdam, The Netherlands.
Bianca ScacciatiFondazione IRCCS Istituto Nazionale dei Tumori, INT, Milano, Italy.ORCID 0000-0002-3543-6176
EU NAVIGATE
Lieve Van den BlockEnd-of-Life Care Research Group, Vrije Universiteit Brussel & Universiteit Gent, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystematic adaptation of evidence-informed interventions is critical for effective transfer across settings. Public health palliative care interventions pose unique challenges because of their complexity and embedding in dynamic, real-life settings. The ADAPT guidance provides a comprehensive framework for systematically adapting evidence-informed health interventions, yet its application in public health palliative care remains unexplored.

aimWithin the EU NAVIGATE project, this study describes the international adaptation process of a Canadian navigation program supporting older people with cancer experiencing declining health, for implementation in six European countries. It also reflects on the methodological insights gained from applying the ADAPT guidance in public health palliative care.

designUsing an iterative five-stage multi-method approach, we followed the ADAPT guidance and its recommended frameworks. Stage 1 assessed context-intervention fit and identified core and adaptable components of the original intervention. Stage 2 adapted implementation materials, while stage 3 involved a contextual analysis. Stage 4 focused on adapting the training for implementers, and stage 5 reviewed feasibility.

resultsThe ADAPT guidance proved flexible and useful, though systematic adaptation posed challenges due to the unique complexities of public health palliative care interventions. These included balancing intervention integrity with cultural sensitivities and local juridical regulations regarding end of life. Our process addressed these challenges through contextual assessments, identifying core components, engaging with original developers, and collaboration between local and international adaptation teams.

conclusionsA systematic adaptation process, guided by the ADAPT guidance is feasible, but transferring public health palliative care interventions requires careful methodological, contextual, and conceptual considerations.

Indexed as

NeoplasmsPalliative CarePublic HealthAgedCanadaEuropeFemaleHumansMaleadaptationImplementation scienceinternationalintervention studypalliative carepublic health

Identifiers

PMID40105050
PMCPMC12084666

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.