Evidence map›Paper›PMID 40105033›Full record

ArticleJournal of applied clinical medical physics2025

Modelling of a double-scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer.

Rasmus Klitgaard, Lars Fredrik Fjæra, Camilla Hanquist Stokkevåg, Perry Johnson, Mark Artz, Nancy Price Mendenhall, Curtis Bryant, Ludvig Paul Muren

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rasmus KlitgaardDanish Centre for Particle Therapy, Aarhus University, Aarhus N, Denmark.ORCID https://orcid.org/0009-0000-5382-6592
Lars Fredrik FjæraDepartment of Medical Physics, Oslo University Hospital, Oslo, Norway.
Camilla Hanquist StokkevågDepartment of Physics and Technology, University of Bergen, Bergen, Norway.
Perry JohnsonDepartment of Radiation Oncology, College of Medicine, University of Florida Health, Jacksonville, Florida, USA.
Mark ArtzDepartment of Radiation Oncology, College of Medicine, University of Florida Health, Jacksonville, Florida, USA.
Nancy Price MendenhallDepartment of Radiation Oncology, College of Medicine, University of Florida Health, Jacksonville, Florida, USA.
Curtis BryantDepartment of Radiation Oncology, College of Medicine, University of Florida Health, Jacksonville, Florida, USA.
Ludvig Paul MurenDanish Centre for Particle Therapy, Aarhus University, Aarhus N, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe dose-averaged linear energy transfer (LET PURPOSE: The initial aim of this study was to implement a MC code allowing for LET

methodsThe components of a passive scattered clinical treatment nozzle used for delivery of extended field ranges, with two associated modulation wheels, were implemented into an existing FLUKA MC framework for LET

resultsThe range differences were below 1 mm for all SOBP scenarios used for calibration. For 9 of 11 SOBP scenarios, the modulation width differences were below 2 mm. For the patient simulations, the mean gamma pass rates (3 mm/3%) were at least 98% in the PTV, bladder, and rectum. Comparing anterior to posterior field configurations, the mean LET

conclusionA MC code allowing for accurate calculations of dose and LET

Indexed as

Linear Energy TransferMonte Carlo MethodProstatic NeoplasmsProton TherapyRadiotherapy Planning, Computer-AssistedComputer SimulationHumansMaleOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-ModulatedRelative Biological EffectivenessScattering, RadiationFLUKAlinear energy transferMonte Carloprostate cancerproton therapy

Identifiers

PMID40105033
PMCPMC12148760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.