Evidence map›Paper›PMID 40104891›Full record

ArticleVeterinary medicine and science2025

Impact of Zinc Hydroxychloride and Oxide Nanoparticles on Broiler Chicken Growth, Gut Microbiota, Immunity and Serum Biochemistry.

Ahmad Taregh Hosein, Majid Toghyani, Mehdi Shahsavan

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmad Taregh HoseinDepartment of Animal Science, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
Majid ToghyaniDepartment of Animal Science, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.ORCID 0000-0003-0470-856X
Mehdi ShahsavanDepartment of Animal Science, Food Science and Animal Science Faculty, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Ahvaz, Iran.ORCID 0000-0003-0459-016X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUse of more efficient sources of zinc (Zn) in corn-soybean basal diet improves the productivity in the absence of growth promoters.

objectiveThis study aimed to compare the effects of different forms of Zn (hydroxychloride: OHCl, oxide nanoparticles: ONPs) on performance and physiological parameters in broiler chickens.

methodsTreatments included control (without use of ZnOHCl and ZnONPs) and three levels of zinc (40, 80 and 110 mg/kg of diets) as either ZnOHCl or ZnONPs.

resultsThe body weight gain and feed conversion ratio for broilers fed with all levels of ZnOHCl, respectively, were greater and smaller than those of ZnONPs and control groups in the entire experiment (p < 0.05). Broilers fed with 110 mg ZnOHCl/kg benefited from the highest anti-Newcastle antibody titre and the lowest breast drip loss, whereas the heaviest relative weight of lymphatic organs and the smallest number of breast muscle pH were relevant to chickens fed with 110 mg ZnONPs/kg (p < 0.05). All levels of either ZnOHCl or ZnONPs caused better humoral immunity and the villus height:crypt depth than the control group (p < 0.05). However, all treatments had a similar effect on the relative weights of internal organs, the heterophil:lymphocyte, anti-influenza antibody titre, percentages of fat, dry matter and crude protein of breast meat, intestinal microbiota and serum biochemistry of broilers (p > 0.05).

conclusionTo sum up, supplementation of ZnOHCl in broilers' diets up to 110 mg was more efficient than ZnONPs in most responses relevant to immunology, growth performance and meat quality.

Indexed as

ChickensChloridesGastrointestinal MicrobiomeNanoparticlesZinc CompoundsZinc OxideAnimal FeedAnimalsDietDietary SupplementsDose-Response Relationship, DrugMaleRandom AllocationZincChloridesZincZinc CompoundsZinc Oxidebroilerimmunityperformancezinc hydroxychloridezinc oxide nanoparticlezinc sources

Identifiers

PMID40104891
PMCPMC11920725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.