Evidence map›Paper›PMID 40104881›Full record

ArticleVeterinary medicine and science2025

Effects of Hydrogen-Rich Water on Growth, Redox Homeostasis and Hormonal, Histological and Immune Systems in Rats Exposed to High Cage Density Stress.

Buket Boğa Kuru, Mustafa Makav, Mushap Kuru, Şükran Yediel Aras, Ebru Karadağ Sarı, Menekşe Bulut, Duried Alwazeer, Fikret Bektaşoğlu, Mükremin Ölmez, Turgut Kırmızıbayrak and 1 more

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Buket Boğa KuruDepartment of Animal Breeding and Husbandry, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.
Mustafa MakavDepartment of Physiology, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.ORCID 0000-0003-1879-8180
Mushap KuruDepartment of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.ORCID 0000-0003-4409-251X
Şükran Yediel ArasDepartment of Midwifery, Faculty of Health Sciences, Kafkas University, Kars, Türkiye.
Ebru Karadağ SarıDepartment of Histology-Embryology, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.
Menekşe BulutDepartment of Food Engineering, Faculty of Engineering, Iğdır University, Iğdır, Türkiye.
Duried AlwazeerDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Iğdır University, Iğdır, Türkiye.
Fikret BektaşoğluDepartment of Animal Breeding and Husbandry, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.
Mükremin ÖlmezDepartment of Animal Nutrition and Nutritional Diseases, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.
Turgut KırmızıbayrakDepartment of Animal Breeding and Husbandry, Faculty of Veterinary Medicine, Kafkas University, Kars, Türkiye.
Tyler W LeBaronDepartment of Kinesiology and Outdoor Recreation, Southern Utah University, Cedar City, Utah, USA.ORCID 0000-0001-9164-6728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated the impact of drinking hydrogen-rich water (HRW) on growth performance, organ weights, thiol/disulphide homeostasis, oxidative status and some hormonal, histopathological and immunohistochemical changes in rats fed in a restricted housing environment.

methodsThe eight groups (each group [male/female] eight rats) comprised two control, two hydrogen, two stress and two stress + hydrogen. All animals were given feed and water ad libitum for 3 months. Control and HRW group rats were calculated according to weight and housed according to the Guide's housing condition. The stress group and stress + HRW group were housed in half the area of the Guide's housing condition according to their weight. The animal's weekly body weights were measured throughout the study. The animals were sacrificed in accordance with ethical rules. Then, biochemical analyses were performed on thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), cortisol, parathyroid hormone (PTH) and calcium (Ca

resultsResults showed that live weight gain was higher in the HRW groups than in the stress group. Oxidant status in biochemical analyses decreased in the stress + HRW group compared to the stress group. TSH decreased in the stress group. FT4, cortisol and Ca

conclusionsThe stress-related physiological parameters were reduced in the HRW + stress group compared to the stress group. HRW could be suggested when the organism is found in stressful conditions.

Indexed as

Drinking WaterHydrogenStress, PhysiologicalAnimalsFemaleHomeostasisHousing, AnimalMaleOxidation-ReductionRatsRats, WistarDrinking WaterHydrogengrowth performance | hydrogen‐rich water | molecular hydrogen | oxidative status | stress

Identifiers

PMID40104881
PMCPMC11920740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.