ReviewTranslational cancer research2025
Cryoablation for breast cancer: a narrative review of advances, clinical applications, and future challenges.
Review in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Cryoablation in the treatment of early breast cancer: a comprehensive analysis.Frontiers in oncology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: Breast cancer remains one of the most common malignant tumors affecting women, with its incidence continuing to rise in recent years. Cryoablation, a minimally invasive technique, has emerged as a promising alternative to conventional surgical excision. Its advantages include high precision, rapid recovery, suitability for local anesthesia, and the potential to activate the immune system, making it an appealing option for patients who are either unwilling or unable to undergo conventional surgical procedures. The objective of this narrative review is to assess the progress and current status of cryoablation in the treatment of breast cancer, providing a comprehensive overview of its technological advances and clinical applications, including device development, mechanisms, surgical procedures, indications, and clinical outcomes for different tumour types. In addition, the article discusses the use of cryoablation in combination with immunotherapy and the challenges ahead. Methods: This study conducted a literature review by searching the PubMed and Web of Science databases to identify the latest research findings in the field of cryoablation technology and breast cancer treatment. Based on these findings, a narrative review was generated. Key Content and Findings: This article presents the mechanisms, devices, and surgical procedures of cryoablation, affirming its safety and efficacy in the clinical treatment of breast cancer. Additionally, it explores the challenges associated with combining cryoablation with immunotherapy to prevent tumor recurrence. As technological advancements continue, it is anticipated that more extensive clinical trials will be conducted to validate the broader application of cryoablation in breast cancer treatment, addressing the limitations of currently available small-scale studies. This progress will aid in selecting more effective treatment strategies for breast cancer patients. Conclusions: Cryoablation has been proven to be a unique and effective approach for treating early-stage, advanced, and inoperable breast cancer patients, demonstrating favorable therapeutic outcomes. Additionally, cryoablation can enhance anti-tumor immune responses, and its combination with immunotherapy and nanomedicine shows promise in preventing tumor recurrence. As a result, cryoablation is gradually becoming a viable alternative to traditional surgical methods for breast cancer treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.