ArticlePNAS nexus2025
Natural-selected plastics biodegradation species and enzymes in landfills.
Article in PNAS nexus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Discovering PETases: An Interlink Between Engineering Enzymes and Microbiomes.Environmental microbiology · 2026Review
- Engineered microbes to enable a circular economy for biodegradable plastics.Frontiers in microbiology · 2026Review
- Towards site-specific information on PET degrading enzymes using NMR near operational temperature.Scientific reports · 2025Article
- Widespread distribution of bacteria containing PETases with a functional motif across global oceans.The ISME journal · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biodegradation is a promising and environmentally friendly strategy for plastic pollution management. Landfills decompose municipal solid waste, including almost 50% of global plastic debris and even some of the oldest synthetic plastics, fostering naturally selected plastic biodegradation. Herein, we present a global collection of plastic biocatalytic enzymes from landfills using metagenomics and machine learning. Metagenomic analysis identified 117 plastic-degrading genes, with 39 incorporated in 22 prokaryotic metagenome-assembled genomes (MAGs). A machine-learning approach predicted 978,107 candidate plastic-degrading genes, 712 of which were encoded respectively by 150 MAGs. Our results highlight landfills as reservoirs of diverse, naturally selected plastic-degrading microbes and enzymes, serving as references and/or models for biocatalysis engineering and in situ bioremediation of plastic pollution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.