ArticleNeurobiology of sleep and circadian rhythms2025
Association of restless legs syndrome and obesity: A sub-population of the MASHAD cohort study.
Article in Neurobiology of sleep and circadian rhythms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Smoking and risk of restless leg syndrome: a systematic review, meta-analysis, and Mendelian randomisation.Journal of global health · 2026Pooled it
- Effects of Bariatric Surgery on Sleep Disorder Symptoms and Sleep Quality.Obesity surgery · 2025Article
- Sleep and Stroke-An Overlooked Bidirectional Influence: Why Should Sleep and Vascular Neurologists Work Closer?Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Restless Legs Syndrome (RLS), as a relatively unknown sleep disorder, often associated with obesity. The purpose of this study was to examine the relationship between RLS and different definitions of obesity within the Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort study population. Methods: A total of 1006 subjects, with an average age of 57 (51.75-63.00) years old, were randomly selected from the MASHAD cohort study phase II. This sample included 449 males and 557 females, who were contacted by phone to inquire about RLS. Anthropometric measurements such as weight, height, waist circumference (WC), and hip circumference (HC) were taken. Central obesity was defined as a WC > 90 cm for men and >85 cm for women, as well as a waist-to-hip ratio (WHR) greater than 0.90 for men and 0.85 for women. Statistical analyses were conducted using R version 4.3.2 for Windows, with a significance level set at a two-sided P-value<0.05. Chi-squared and Fisher's exact tests were used to compare the categorical variables between two study groups. Logistic models applied to evaluate the association between RLS and BMI while adjusting for age effects. Results: The study found a significant relationship between RLS and employment status (p-value = 0.04), marital status (p-value = 0.05), and BMI (p-value<0.001). The results showed that in the total population, the OR of RLS in subjects having BMI>30 kg/m Conclusion: There was a significant association between BMI and RLS. A BMI>30 kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.