Evidence map›Paper›PMID 40104544›Full record

ArticleFrontiers in veterinary science2025

Case report: Clinical fungal endocarditis as a component of presumptive systemic aspergillosis infection in a dog.

L Kay Drake

Abstract readCase Reports
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

L Kay DrakeVeterinary Specialty Hospital - North County, Internal Medicine, Ethos Veterinary Health, San Marcos, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 2-year-old 26-kilogram female spayed mixed breed dog presented for acute azotemia, a new heart murmur, anorexia, and lethargy. Further workup revealed marked azotemia with bilateral renal changes on abdominal ultrasound. An echocardiogram detected vegetative lesion on the mitral valve, consistent with infective endocarditis. The patient tested positive for the galactomannan antigen (Aspergillus EIA Galactomannan Test by MiraVista) leading to a presumptive diagnosis of systemic aspergillosis. Despite aggressive treatment, the patient continued to deteriorate and developed signs of dyspnea which temporarily improved with furosemide therapy (VetOne; Boise, ID). After humane euthanasia, postmortem evaluation confirmed fungal endocarditis. This is the first published case of clinical endocarditis in a dog suspected to be from aspergillosis based on both antemortem diagnostics and postmortem pathology. Thus, this case serves to further our understanding of systemic aspergillosis manifestations which in turn can aid in prompt diagnosis and treatment of the condition.

Indexed as

aspergillosisaspergillusdogendocarditisfungal

Identifiers

PMID40104544
PMCPMC11913859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.