Evidence map›Paper›PMID 40104520›Full record

ArticleChina CDC weekly2025

Association Between Incorrect Use of Pre- and Post-Exposure Prophylaxis and HIV infection Among Men Who Have Sex with Men - Shenzhen City, Guangdong Province, China, 2021-2023.

Zijie Yang, Jiachun Chen, Lan Wei, Delei Dai, Hu Tang, Yan Zhang, Wei Xie, Shaochu Liu, Wei Tan, Xiangdong Shi and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zijie YangSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Jiachun ChenSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Lan WeiSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Delei DaiSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Hu TangSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Yan ZhangSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Wei XieSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Shaochu LiuSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Wei TanSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Xiangdong ShiSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Chenli ZhengSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Xiaohong YuanSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Zhongliang XuShenzhen Nanshan Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Wei YeShenzhen Nanshan Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.
Jin ZhaoSTD & AIDS Control and Prevention Section, Shenzhen Center for Disease Control and Prevention, Shenzhen City, Guangdong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is already known about this topic?: Preexposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) have been proven effective in preventing human immunodeficiency virus (HIV) transmission. What is added by this report?: Men who have sex with men (MSM) who incorrectly used PrEP/PEP demonstrated higher HIV positivity rates compared to both correct users and non-users. Since PrEP/PEP users are more likely to engage in unprotected anal intercourse (UAI), incorrect use of these prophylactic measures may constitute a significant risk factor for HIV transmission among MSM. What are the implications for public health practice?: It is crucial to implement strategies that guide MSM toward correct PrEP/PEP utilization while emphasizing that these prophylactic measures should not be considered substitutes for condom use.

Indexed as

HIV/AIDSMen who have sex with menPost-Exposure ProphylaxisPre-Exposure Prophylaxis

Identifiers

PMID40104520
PMCPMC11911659

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.