ArticleChina CDC weekly2025
The Impact of ART on Stillbirth and Neonatal Death Among HIV-positive Pregnant Women - Yunnan Province, China, 2013-2022.
Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: This study assessed the impact of antiretroviral therapy (ART) on stillbirth and neonatal mortality and investigated associated risk factors among Human immunodeficiency virus-positive (HIV-positive) pregnant women in Yunnan, China during 2013-2022. Methods: Data from the National Information System of Integrated Prevention of Mother-to-Child Transmission of HIV, Syphilis, and Hepatitis B Program (PMTCT) were analyzed to determine stillbirth and neonatal mortality rates. Multivariate Poisson regression was employed to identify risk factors associated with stillbirth and neonatal outcomes. Results: Among 9,563 HIV-positive women with singleton pregnancies in Yunnan Province during 2013-2022, 9,404 (98.34%) received ART during pregnancy, while 159 (1.66%) did not. There were 9,421 live births, 76 stillbirths, and 66 neonatal deaths, yielding a stillbirth rate (SBR) of 8.07‰ and neonatal mortality rate (NMR) of 7.01‰. The SBR was significantly lower in pregnancies where ART was used ( Conclusions: Stillbirth and neonatal mortality rates were elevated among mothers who did not receive ART during pregnancy compared to those who did. These findings emphasize the importance of ART during pregnancy, particularly since several mortality risk factors are amenable to intervention.
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