Evidence map›Paper›PMID 40104229›Full record

ArticleActa clinica Croatica2024

COMPARISON OF ABBOTT REAL TIME SARS-COV-2 ASSAY AND LIFERIVER NOVEL CORONAVIRUS REAL TIME MULTIPLEX KIT FOR THE RT-PCR BASED DETECTION OF SARS-COV-2 FROM NASOPHARYNGEAL SWABS.

Jelena Stojčević-Maletić, Iva Barjaktarović, Mirjana Đerić, Velibor Čabarkapa, Vladimir Petrović, Aleksandra Patić, Slobodanka Bogdanović-Vasić

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta clinica Croatica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jelena Stojčević-MaletićUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Iva BarjaktarovićUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Mirjana ĐerićUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Velibor ČabarkapaUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Vladimir PetrovićUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Aleksandra PatićUniversity of Novi Sad, Faculty of Medicine, Novi Sad, Serbia.
Slobodanka Bogdanović-VasićŠabac High School of Medical and Business-Technology School of Professional Studies, Šabac, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to compare performance of two authorized tests, the Abbott Real Time SARS-CoV-2 (ACOV) assay (Abbott Molecular Inc., North Chicago, IL, USA) and Liferiver Novel Coronavirus Real Time Multiplex RT-PCR (Liferiver 2019-nCoV) kit (BioVendor Group, Brno, Czech Republic), and to determine whether the selection of targeted genes has an impact on test specificity. We included 105 nasopharyngeal swabs from adult individuals with symptoms or suspected of coronavirus disease 2019 (COVID-19), aged from 26 to 91 years, previously tested by the ACOV and subsequently tested by the Liferiver 2019-nCoV. In this comparative analysis, we found that the ACOV assay detected more cases of COVID-19 infection than the Liferiver 2019-nCoV assay. The Liferiver 2019-nCoV kit showed a high level of agreement with the ACOV assay. The positive percent agreement was 88.89% (95% confidence intervals (95% CI): 77.42%-100.0%), and the kappa coefficient (kappa) was 0.901 (95% CI: 0.817-0.985). The negative percent agreement was 94.12% (95% CI: 89.74%-98.50%), while 4.76% of SARS-CoV-2 cases were false-negative using the Liferiver test. However, due to the possible false-negative results using the Liferiver 2019-nCOV test, we recommend complete testing with the ACOV assay.

Indexed as

COVID-19COVID-19 Nucleic Acid TestingMultiplex Polymerase Chain ReactionNasopharynxReal-Time Polymerase Chain ReactionSARS-CoV-2AdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedReagent Kits, DiagnosticSensitivity and SpecificityReagent Kits, DiagnosticMolecular diagnosticsPolymerase chain reactionRNA isolationVirus detection

Identifiers

PMID40104229
PMCPMC11912847

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.