Evidence map›Paper›PMID 40103964›Full record

ArticleInternational journal of ophthalmology2025

Dynamic changes of spontaneous brain activity in patients after LASIK: a resting-state fMRI study.

Hui Zhang, Zi-Song Xu, Jin-Yu Hu, Zhen-Zhe Liu, Lei Zhong, Liang-Qi He, Cheng Chen, Xiao-Yu Wang, Hong Wei, Yan-Mei Zeng and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hui ZhangNanchang Bright Eye Hospital, Nanchang 330000, Jiangxi Province, China.
Zi-Song XuDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Jin-Yu HuDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Zhen-Zhe LiuDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Lei ZhongDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China.
Liang-Qi HeDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Cheng ChenDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Xiao-Yu WangDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Hong WeiDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Yan-Mei ZengDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Qian LingDepartment of Ophthalmology, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi Province, China.
Xu ChenOphthalmology Centre of Maastricht University, Maastricht 6200MS, Limburg Provincie, the Netherlands.
Yi-Xin WangSchool of Optometry and Vision Science, Cardiff University, Cardiff, CF24 4HQ, Wales, UK.
Yi ShaoDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Eye Diseases, Shanghai Key Laboratory of Ocular Fundus Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai 200080, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate changes in local brain activity after laser assisted

methodsThe resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 15 myopic patients who underwent LASIK and 15 matched healthy controls. This method was selected to calculate the corresponding dALFF values of each participant, to compare dALFF between the groups and to determine whether dALFF distinguishes reliably between myopic patients after LASIK and HCs using the linear support vector machine (SVM) permutation test (5000 repetitions).

resultsdALFF was lower in POL than in HCs at the right precentral gyrus and right insula. Classification accuracy of the SVM was 89.1% (

conclusionThe activity of spontaneous neurons in the right precentral gyrus and right insula of myopic patients change significantly after LASIK. SVM can correctly classify POL patients and HCs based on dALFF differences.

Indexed as

amplitude of low-frequency fluctuationsdynamic brain activitylaser assisted in situ keratomileusisresting-state functional magnetic resonance imagingsupport vector machine

Identifiers

PMID40103964
PMCPMC11865659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.