ArticleInternational journal of ophthalmology2025
High-altitude effect on corneal endothelial cells and prognosis in patients with cataract surgeries: a propensity score matched analysis.
Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Beyond the Cornea: Systemic Diseases and Their Impact on Endothelial Health-A Narrative Review.Journal of clinical medicine · 2026Review
- Relationship between Central Corneal Thickness and Endothelial Cell Density in Individuals with Primary Glaucoma and the General Population Living at High Altitudes.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo compare analysis of the impact of high altitude on corneal endothelial cells, and the prognosis in patients with cataract surgeries.
methodsTotally 265 plateau patients with cataract surgeries performed between January 2019 and July 2022 (average altitude=3000 m), and 524 plain patients with cataract surgeries performed between January 2020 and July 2022 were included. The propensity score matching (PSM) method was applied to match the basic information of patients in both regions on a 1:1 basis. Corneal endothelial cell density (ECD), coefficient of variation (CV), hexagonal cell ratio (HEX), duration of surgery, and pre- and postoperative visual acuity (VA) were compared retrospectively, and correlation tests were done.
resultsTotally 223 pairs have been matched successfully. The HEX in the plateau group was higher than that in the plain group (61.95%±6.191%
conclusionThe relative hypoxic environment of the plateau does not promote the apoptosis of corneal endothelial cells, but may lead to the compensatory increase of their functions. In plateau patients, no significant associations are found between the poor VA and the corneal endothelial functions early after cataract surgeries.
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