Evidence map›Paper›PMID 40103911›Full record

ArticlePakistan journal of medical sciences2025

Effect of 0.8mg/ml Losartan on Corneal Opacities.

Aisha Fawad, Waqar Muzaffar, Unnab Anjum, Mahad Naseer Amer

Abstract readCase Reports
In one paragraph

Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aisha FawadAisha Fawad, FCPS (Ophth), FRCSGlas (Ophth) Associate Professor of Ophthalmology, Refractive Department, National University of Medical Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Waqar MuzaffarWaqar Muzaffar, FCPS (Ophth), FRCS (Edinburgh), CST (UK) Professor and Dean of Ophthalmology, National University of Medical Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.
Unnab AnjumUnnab Anjum Resident Ophthalmology, National University of Medical Sciences, Rawalpindi, Pakistan.
Mahad Naseer AmerMahad Naseer Amer Resident Ophthalmology, National University of Medical Sciences, Rawalpindi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Losartan, commonly used as an angiotensin receptor II inhibitor for hypertension, has recently revealed additional therapeutic properties. Studies demonstrate its potential in treating liver fibrosis, mitigating heart disease secondary to radiation, reducing skin scar formation, and even reversing renal cortical fibrosis. In a specific case, a female patient suffering from persistent bilateral nummular keratitis and corneal opacities experienced significant improvement in her left eye after using 0.8mg/ml Losartan eye drops. Untreated right eye showed no change. Based on the positive outcome, patient was offered same treatment in her right eye as well with monthly follow-ups, which she happily accepted. The stark contrast between the treated and untreated eye highlights the promising role of Losartan in treating corneal opacities.

Indexed as

Corneal opacitykeratitisLosartan

Identifiers

PMID40103911
PMCPMC11911758

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.