Evidence map›Paper›PMID 40103849›Full record

ArticleBrain & spine2025

The current state of cranioplasty in Europe - Results from a European cranioplasty survey.

Paul Vincent Naser, Parmenion Tsitsopoulos, Friederike Zacharias, Ana M Castaño-Leon, Andras Buki, Bart Depreitere, Thomas Van Essen, Tommi K Korhonen, Harry Mee, Iftakher Hossain and 12 more

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Paul Vincent NaserHeidelberg University Hospital, Department of Neurosurgery, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Parmenion TsitsopoulosDepartment of Neurosurgery, Hippokration General Hospital, Aristotle University School of Medicine, Konstantinoupoleos 49, 54642, Thessaloniki, Greece.
Friederike ZachariasHeidelberg University Hospital, Department of Neurosurgery, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Ana M Castaño-LeonNeurosurgery Department, Av. Cordoba S/n, 28041, Madrid, Spain.
Andras BukiDepartment of Neurosurgery Örebro University Hospital, Södra Grev Rosengatan 42, 70362, Örebro, Sweden.
Bart DepreitereNeurosurgery, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Thomas Van EssenNeurosurgery, Leiden University Medical Center, Albinusdreef 2, 2333, ZA, Leiden, Netherlands.
Tommi K KorhonenNeurosurgery, OYS Neurocenter, Oulu University Hospital, Kajaanintie 50, 90029, Oulu, Finland.
Harry MeeClinical Neurosciences, Addenbrookes Hospital, CB2 0QQ, Cambridge, United Kingdom.
Iftakher HossainNeurocenter, Department of Neurosurgery, Turku University Hospital, Hämeentie 11, 20521, Turku, Finland.
Jussi PostiNeurocenter, Department of Neurosurgery, Turku University Hospital, Hämeentie 11, 20521, Turku, Finland.
Laura LippaUOC Neurosurgery, ASST Ospedale Niguarda, Milano, Piazza Dell'ospedale Maggiore 1, 20162, Milan, Italy.
Marios C PapadopoulosNeurosurgery, Atkinson Morley Wing, St. George's Hospital, Blackshaw Road, SW17 0QT, London, United Kingdom.
Nicole TerpolilliLudwig-Maximilians-Universität Munich, Department of Neurosurgery, Marchioninistr. 15, 81377, Munich, Germany.
Niklas MarklundDepartment of Clinical Sciences Lund, Neurosurgery, Klinikgatan 17A, EA-blocket, 4th Floor, 22185, Lund, Sweden.
Ondra PetrDepartment of Neurosurgery, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.
Peter TothDepartment of Neurosurgery, University of Pecs, Hubgary, Ret street 2, Pecs, Hungary.
Teemu LuotoDepartment of Neurosurgery, Tampere University Hospital, PL 2000, 33521, Tampere, Poland.
Sandro M KriegHeidelberg University Hospital, Department of Neurosurgery, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Andreas W UnterbergHeidelberg University Hospital, Department of Neurosurgery, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Alexander YounsiHeidelberg University Hospital, Department of Neurosurgery, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
European Cranioplasty Survey Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cranioplasty, a surgical procedure to restore skull integrity and aesthetic contour following decompressive craniectomy, poses challenges in material selection and timing, driven by the lack of guidelines and ongoing regulatory changes. Research question: This study aimed to provide an overview of current cranioplasty practices in Europe, explicitly addressing a potential shift towards alloplastic materials and the management of patients with concomitant hydrocephalus. Material and methods: An online survey was conducted among European neurosurgical centers from January to March 2024, collecting data on material preferences, timing of procedures, and management strategies for cranioplasty. Descriptive and statistical analyses were performed on 110 complete responses. Results: Respondents favored alloplastic materials over autologous bone for cranioplasty, citing regulatory constraints and reduced infection risk as primary reasons. Variability was observed in the timing of procedures and the management of patients with hydrocephalus, with most centers adopting staged approaches. Discussion and conclusion: The shift towards alloplastic materials in cranioplasty reflects regulatory pressures rather than material-specific considerations. Despite variability in practice, our findings underscore the need for standardized guidelines and further research to optimize patient outcomes. This study provides valuable insights into current practices and highlights areas for future investigation in cranioplasty.

Indexed as

Alloplastic materialsAutologous boneCranioplastyEuropean surveyHydrocephalus managementRegulatory changes

Identifiers

PMID40103849
PMCPMC11914825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.