ArticleOphthalmology science
Radiomic Feature Extraction from OCT Angiography of Idiopathic Epiretinal Membranes and Correlation with Visual Acuity: A Pilot Study.
Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Radiomics-based fundus autofluorescence analysis in central serous chorioretinopathy-MICRoN report number twelve.Scientific reports · 2026Article
- Radiomics-Based Fundus Photography Analysis in Diabetic Retinopathy.Translational vision science & technology · 2026Article
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Authors and funding
12 authors.
Funding
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Abstract
Purpose: To explore the correlation between radiomics features extracted from OCT angiography (OCTA) of epiretinal membranes (ERMs) and baseline best-corrected visual acuity (BCVA). Design: Retrospective observational monocentric study. Participants: Eighty-three eyes affected by idiopathic ERMs, categorized into low (≤70 letters) and high (70 letters) BCVA groups. Methods: The central 3 × 3 mm Main Outcome Measures: The 4 selected informative radiomic features were as follows: the difference average (glcm_DifferenceAverage), quantifying the average difference in gray-level between neighboring pixels; the informational measure of correlation (glcm_Imc1), giving information about the spatial correlation of pixel intensities inside the image; the long run low gray-level emphasis (glrlm_LongRunLowGrayLevelEmphasis), highlighting long segments of low gray-level values within the image; and the large area emphasis (glszm_LargeAreaEmphasis), which quantifies the tendency for larger zones of uniform intensity to occur. Results: No features exhibited a statistically significant difference between low and high BCVA values for the superficial and deep retinal slabs. Conversely, in the choriocapillaris layer, the glcm_DifferenceAverage and glcm_Imc1 features were significantly higher in the high BCVA group ( Conclusions: Radiomics features of the choriocapillaris in idiopathic ERMs showed a correlation with BCVA, with lower structural complexity and higher homogeneity, together with the presence of homogeneous areas with low-intensity pixel values, reflecting flow voids due to reduced microvascular perfusion, and were correlated with lower visual acuity. Financial Disclosures: The author(s) have no proprietary or commercial interest in any materials discussed in this article.
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