Evidence map›Paper›PMID 40103800›Full record

ArticleEuropean heart journal. Case reports2025

Left atrial veno-arterial extracorporeal membrane oxygenation as a bridge to surgical or percutaneous closure of post-myocardial infarction ventriculoseptal defects: a case series.

Raef Fadel, Jessica Elderkin, Hussayn Alrayes, Gennaro Giustino, Tiberio Frisoli, Mir Babar Basir, Dimitrios Apostolou, Pedro Villablanca

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Raef FadelCardiovascular Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.ORCID https://orcid.org/0000-0002-9243-5196
Jessica ElderkinWayne State University School of Medicine, 2799 W Grand Blvd, Detroit, MI 48202, USA.
Hussayn AlrayesStructural Heart Disease, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.
Gennaro GiustinoStructural Heart Disease, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.
Tiberio FrisoliStructural Heart Disease, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.
Mir Babar BasirCardiovascular Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.
Dimitrios ApostolouCardiac Surgery, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.
Pedro VillablancaStructural Heart Disease, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Post-myocardial infarct (MI) ventricular septal defect (VSD) is a rare and severe complication of an acute MI with high mortality rate. The use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to surgical or percutaneous repair in cardiogenic shock secondary to post-MI-VSD has been published, but is limited to small case series primarily utilizing surgical ECMO, with the main drawback of potentially increasing afterload and left ventricle pressure, further worsening VSD shunting. Left-atrial VA-ECMO (LAVA-ECMO) can potentially absolve this concern given that it utilizes bi-atrial drainage through a trans-septal fenestrated cannula. Case summary: Five patients were included in this series, all with VSD secondary to MI, and all managed with LAVA-ECMO as a bridge to repair. Average age was 62 ± 4.2 years, body mass index of 29.4 ± 4.5 kg/m Discussion: This case series reports the successful use of LAVA-ECMO as a bridge to MI-VSD repair in patients with cardiogenic shock. Left-atrial VA-ECMO serves as a convenient approach to managing patients with MI-VSD related cardiogenic shock as it is implanted percutaneously, and can be done at the time of shock diagnosis, during right heart catheterization by trained interventionists.

Indexed as

Cardiogenic shockCase reportECMOPost-myocardial infarct ventricular septal defect

Identifiers

PMID40103800
PMCPMC11914317

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.