Evidence map›Paper›PMID 40103748›Full record

ArticleThe journal of allergy and clinical immunology. Global2025

Oral microbiota related to allergy in Norwegian adults.

Mikyeong Lee, Hilde Kristin Vindenes, Farnaz Fouladi, Rajesh Shigdel, James M Ward, Shayamal D Peddada, Stephanie J London, Randi Jacobsen Bertelsen

Abstract read
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mikyeong LeeImmunity Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Hilde Kristin VindenesDepartment of Occupational Medicine, Haukeland University Hospital, Bergen, Norway.
Farnaz FouladiBiostatistics & Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Rajesh ShigdelDepartment of Clinical Science, University of Bergen, Bergen, Norway.
James M WardIntegrative Bioinformatics Support Group, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Shayamal D PeddadaBiostatistics & Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Stephanie J LondonImmunity Inflammation and Disease Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC.
Randi Jacobsen BertelsenDepartment of Clinical Science, University of Bergen, Bergen, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oral microbiome composition has been linked to onset and progression of several localized and systemic diseases. Associations with allergy in adults have been less explored. Objective: We sought to identify oral microbiota associated with allergy outcomes in adults using high-throughput sequencing data. Methods: We characterized bacterial communities of gingival samples from 453 Norwegian adults (average age, 28 years) using 16S rRNA gene amplicon sequencing. We examined more than 2200 bacterial taxa in relation to self-reported current asthma, eczema, or rhinitis, and seroatopy (IgE > 0.70 kU/L). We used linear regression to determine whether overall bacterial diversity differed by each allergic outcome and analysis of composition of microbiomes with bias correction (ANCOM-BC2) to identify differentially abundant taxa. Results: Less diverse oral bacterial communities were observed ( Conclusions: Bacterial community compositions of oral gingival samples may play a role in allergic outcomes in adults. These findings could contribute to the development of novel treatment strategies.

Indexed as

allergy and immunologyBacteriadysbiosishost microbial interactionsmicrobiome

Identifiers

PMID40103748
PMCPMC11914992

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.