Evidence map›Paper›PMID 40103699›Full record

ReviewIbrain2025

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis.

Xue Zheng, Jing Li, Zhao-Qiong Zhu

Abstract readReview
In one paragraph

Review in Ibrain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xue ZhengDepartment of Anesthesiology Zunyi Matermal And Child Health Care Hospital Zunyi Guizhou China.ORCID 0000-0002-0037-8367
Jing LiDepartment of Cardiothoracic Surgery University Medical Center Regensburg Regensburg Germany.
Zhao-Qiong ZhuDepartment of Anesthesiology Affiliated Hospital of Zunyi Medical University Zunyi Guizhou China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti-inflammatory, antioxidant, antiapoptosis, and other aspects. As the global aging process continues to intensify, diseases of the central nervous system, cardiovascular system, and immune system have brought serious economic and mental burdens to families and have become a major challenge for global public health resources. Many studies have proved that gastrodin may be a potential drug for neurological diseases and ischemic injury but its mechanism of action is still unclear. [Correction added on 19 February 2025, after first online publication: In the preceding sentence, "the treatment of various systemic diseases" has been corrected to "neurological diseases and ischemic injury" in this version.]. In this study, the pharmacological action of gastrodin and the possible mechanism of regulating ferroptosis and pyroptosis were reviewed to provide a new treatment and research direction for clinicians and researchers.

Indexed as

ferroptosisgastrodinpharmacological effectpyroptosis

Identifiers

PMID40103699
PMCPMC11911110

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.