Evidence map›Paper›PMID 40103663›Full record

ArticleAdvances in radiation oncology2025

Fuzzy Analytical Hierarchy Process-based Risk Priority Number Approach in Failure Modes and Effects Analysis for Magnetic Resonance Imaging-guided High-dose-rate Brachytherapy for Gynecologic Cancer.

Jina Chang, Hayeon Kim, Ron Lalonde, Elangovan Doraisamy, John Vargo

Abstract read
In one paragraph

Article in Advances in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jina ChangDepartment of Radiation Oncology, University of Pittsburgh Medical Center, Shadyside Hospital, Pittsburgh, Pennsylvania.
Hayeon KimDepartment of Radiation Oncology, University of Pittsburgh Medical Center, Magee-Women's Hospital, Pittsburgh, Pennsylvania.
Ron LalondeDepartment of Radiation Oncology, University of Pittsburgh Medical Center, Shadyside Hospital, Pittsburgh, Pennsylvania.
Elangovan DoraisamyDepartment of Radiation Oncology, University of Pittsburgh Medical Center, Magee-Women's Hospital, Pittsburgh, Pennsylvania.
John VargoDepartment of Radiation Oncology, University of Pittsburgh Medical Center, Magee-Women's Hospital, Pittsburgh, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Failure modes and effects analysis (FMEA) is commonly used to identify, prioritize, and mitigate potential failure modes (FMs) by assigning a risk priority number (RPN). However, traditional RPN-based FMEA has limitations, particularly when handling the degree of interdependency within processes. To address this, we propose a fuzzy analytical hierarchy process (AHP)-based RPN method, designed to prioritize FMs by accurately weighing risk factors in magnetic resonance imaging (MRI)-guided high-dose-rate brachytherapy (BT) for gynecologic (GYN) cancer. Methods and Materials: A process map covering all steps was developed for MRI-based GYN BT, and potential FMs were identified. Evaluators were given 2 questionnaires, one for conventional FMEA and another for AHP evaluation. For the AHP method, substeps were grouped by job specialty, with identical weights applied to FMs within each specialty group. Fuzzy linguistic terms helped evaluators handle uncertainties, and final fuzzy AHP-based RPN values were calculated by applying weighted risk factor scores. Results: The process map included 6 primary steps, 33 substeps, and 82 FMs. In the fuzzy AHP RPN analysis, the top 5 FMs were identified as incorrect/suboptimal applicator insertion, incorrect applicator reconstruction, dose-volume histogram not meeting the physician's intent, incorrect/missing contours, and applicator/patient movement. By comparison, the conventional FMEA ranked the top 5 as incorrect/missing contours, incorrect/suboptimal applicator insertion, dose-volume histogram not meeting the physician's intent, applicator/patient movement, and incorrect applicator reconstruction. FMs with rank differences of 10 or more between methods were mostly related to applicator insertion and MRI. Conclusions: This study demonstrates the feasibility and effectiveness of a fuzzy AHP-based RPN method for comprehensive FM prioritization, tailored to the clinical workflow of MRI-based GYN BT. Our findings provide a valuable reference for implementing fuzzy AHP-based risk assessment in MRI-guided BT.

Identifiers

PMID40103663
PMCPMC11914780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.