Evidence map›Paper›PMID 40103565›Full record

SynthesisVeterinary medicine and science2025

Cryptosporidium in Rabbits: A Global Systematic Review and Meta-Analysis of Prevalence, Species/Genotypes Distribution and Zoonotic Significance.

Ali Ghorbani, Ali Asghari, Mohammad Reza Mohammadi, Milad Badri, Laya Shamsi, Fatemeh Hanifeh, Behnam Mohammadi-Ghalehbin, Saiyad Bastaminejad

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Prevalence, Genetic Diversity, and Risk Factors ofThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ali GhorbaniDepartment of Microbiology and Virology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Ali AsghariMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID 0000-0002-4005-2687
Mohammad Reza MohammadiDepartment of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Milad BadriMedical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.ORCID 0000-0002-1860-326X
Laya ShamsiDepartment of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Fatemeh HanifehDepartment of Biology, Faculty of Science, Danesh Alborz University, Abyek, Iran.
Behnam Mohammadi-GhalehbinZoonoses Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Saiyad BastaminejadDepartment of Genetics and Molecular Medicine, School of ParaMedicine, Ilam University of Medical Sciences, Ilam, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis systematic review and meta-analysis assessed the global prevalence, species/genotype distribution and zoonotic impact of Cryptosporidium in rabbits.

methodsA systematic search of PubMed, Scopus and Web of Science was performed for studies from 2000 to 25 October 2024 on Cryptosporidium spp. in rabbits. Data on publication/implementation years, prevalence rates, rabbit types, diagnostics, countries and species/genotypes were collected. A meta-analysis with random-effects models estimated overall prevalence and assessed heterogeneity using the I

resultsThis systematic review included 26 studies with 6093 rabbits from 9 countries, revealing a pooled Cryptosporidium spp. prevalence of 9% (95% CI: 6%-13.4%). Three zoonotic species were found in rabbits: Cryptosporidium cuniculus in 18 studies and each of C. parvum and C. andersoni in 1 study. The isolates included 2 genotypes of C. cuniculus (Va, Vb) and 1 genotype of C. parvum (IIc), along with 18 subtypes of C. cuniculus (VaA16, VaA18, VaA31, VbA18, VbA19, VbA21, VbA22, VbA23, VbA24, VbA25, VbA26, VbA28, VbA29, VbA31, VbA32, VbA33, VbA35 and VbA36). Among these, 11 subtypes (VbA19, VbA22-VbA26, VbA28, VbA29 and VbA31-VbA33) are identified as zoonotic. Pet rabbits had the highest Cryptosporidium spp. pooled prevalence at 21.9% (95% CI: 14.7%-31.3%), followed by farmed rabbits at 9.7% (95% CI: 5.1%-17.8%), wild rabbits at 8.8% (95% CI: 4.8%-15.5%) and laboratory rabbits at 1% (95% CI: 0.3%-3.1%), with higher rates noted in Africa and the AFR WHO region.

conclusionsThis study assessed the global distribution of Cryptosporidium spp. in rabbits, highlighting its zoonotic implications. It serves as a key resource for researchers, veterinarians and public health officials for future studies and control strategies.

Indexed as

CryptosporidiosisCryptosporidiumZoonosesAnimalsGenotypePrevalenceRabbitsCryptosporidium sppprevalencerabbitsspeciessubtypessystematic review

Identifiers

PMID40103565
PMCPMC11920741

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.