Evidence map›Paper›PMID 40102985›Full record

Trial reportBMC research notes2025

The effect of povidone-iodine 10% plus levofloxacin 0.5% before cataract surgery: a randomized clinical trial.

Ali Azimi, Mohammad Reza Jafari, Ehsan Namvar, Nasrin Masihpour, Shadi Meshksar

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali AzimiPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Reza JafariShiraz University of Medical Sciences, Shiraz, Iran.
Ehsan NamvarPoostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. namvar.e@gmail.com.
Nasrin MasihpourAhvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Shadi MeshksarShiraz University of Medical Sciences, Shiraz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was designed to assess the efficacy of using povidone-iodine (PVI) 10% and levofloxacin 0.5% about one hour before cataract surgery in minimizing aqueous contamination compared with using PVI 10%. The intervention group received three drops of mixed povidone-iodine and levofloxacin (PVI/Levofloxacin) solution one hour before surgery. After making the corneal incision in cataract surgery, 0.1 cc aqueous humor sample was taken and sent for culture. We compared the intervention group and control group using t-test and chi-square test in SPSS 25(Chicago IL, USA). 147 eyes of 147 patients were analyzed. The intervention and control groups consisted of 72 and 75 patients, respectively. The Control group showed significantly more positive cultures (16 cultures: 22.2%). the intervention group had four positive cultures (5.3%). (P-value = 0.005). Topical levofloxacin 0.5% and povidone-iodine 10% mixture showed promising results in reducing the number of bacteria in the aqueous humor.

Indexed as

Anti-Bacterial AgentsAnti-Infective Agents, LocalCataract ExtractionLevofloxacinPovidone-IodineAgedAged, 80 and overAqueous HumorFemaleHumansMaleMiddle AgedAnti-Bacterial AgentsAnti-Infective Agents, LocalLevofloxacinPovidone-IodineEndophthalmitisLevofloxacinPovidone-iodine

Identifiers

PMID40102985
PMCPMC11921663

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.