Evidence map›Paper›PMID 40102942›Full record

ArticlePorcine health management2025

Comparison of antimicrobial susceptibility of Glaesserella parasuis from different pig production systems in Taiwan between 2015 and 2020.

Wei-Hao Lin, Zhu-Wei Liou, Szu-Min Lin, Cheng-Yao Yang, Chuen-Fu Lin, Yung-Fu Chang, Chao-Nan Lin, Ming-Tang Chiou

Abstract read
In one paragraph

Article in Porcine health management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Triplex Real-Time PCR Assay for Simultaneous Detection ofTransboundary and emerging diseases · 2026
    Article
  2. Frontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei-Hao LinAnimal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan. whlin@mail.npust.edu.tw.
Zhu-Wei LiouAnimal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan.
Szu-Min LinAnimal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan.
Cheng-Yao YangGraduate Institute of Veterinary Pathobiology, College of Veterinary Medicine, National Chung Hsing University, Taichung, 402202, Taiwan.
Chuen-Fu LinAnimal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan.
Yung-Fu ChangDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
Chao-Nan LinAnimal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan.
Ming-Tang ChiouAnimal Disease Diagnostic Center, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung, 912301, Taiwan. mtchiou@mail.npust.edu.tw.

Funding

Ministry of Agriculture, Taiwan, R.O.C. 112AS-2.1.3-AD-U1
6 · The paper itself

Abstract

backgroundGlässer's disease, caused by Glaesserella parasuis (G. parasuis), is a widespread bacterial infection in swine that leads to significant economic losses. G. parasuis, a member of the normal microbiota within the Pasteurellaceae family, exhibits horizontal resistance gene exchange and intracellular invasion capabilities, increasing the risk of developing resistant isolates. Accurate antimicrobial therapy is essential for controlling Glässer's disease. The production systems for exotic crossbred pigs and Taiwan black pigs differ considerably. To inform Glässer disease control and monitor antimicrobial resistance, we assessed the antimicrobial susceptibilities of G. parasuis isolates, analyzed them using normalized resistance interpretation (NRI), and compared findings between the two production systems.

resultsA total of 154 G. parasuis isolates from 106 exotic crossbred pig herds and 48 Taiwan black pig herds were tested against 16 antimicrobial agents between 2015 and 2020. Due to the absence of specific breakpoints for G. parasuis, NRI was utilized to define non-wild-type (non-WT) populations based on minimum inhibitory concentration (MIC) distributions. Non-WT subpopulations of isolates for amoxicillin, ampicillin, ceftiofur, gentamicin, kanamycin, and tiamulin were observed. The highest MIC

conclusionsThis study provides the susceptibility profile of G. parasuis isolates for both exotic crossbred pigs and Taiwan black pigs in Taiwan and highlights potential antimicrobial resistance for aminocyclitol, aminoglycosides, beta-lactams, lincosamides, macrolides, and pleuromulin. Ceftiofur, cephalothin, doxycycline, and florfenicol could be most suitable for treating early-stage Glässer's disease. Nonetheless, increased attention should be paid to the responsible use of antimicrobials in light of the growing threat of antimicrobial resistance.

Indexed as

Antimicrobial susceptibilityGlaesserella parasuisGlässer’s diseaseMinimal inhibitory concentrationPig

Identifiers

PMID40102942
PMCPMC11921561

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.