Evidence map›Paper›PMID 40102830›Full record

ArticleBMC infectious diseases2025

Clinical characteristics, complications, and outcome of brain abscess treated by stereotactic aspiration: a retrospective analysis.

Yuxiang Cai, Jian Liu, Ge Jia, Yonghong Hou, Yanjin Wang

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Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yuxiang CaiDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, P.R. China.
Jian LiuDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, P.R. China.
Ge JiaDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, P.R. China.
Yonghong HouDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, P.R. China.
Yanjin WangDepartment of Neurosurgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, P.R. China. wyjinneuro@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate the clinical presentation, imaging features, and outcome of patients diagnosed with brain abscess and treated by stereotactic aspiration.

methodsWe retrospectively analyzed the medical data of all consecutive patients diagnosed with brain abscess who underwent stereotactic aspiration in our department from 2015 to 2022. The demographic characteristics, clinical presentation, radiological data, microbial aetiology, and outcome were collected and analyzed using t-test or χ

resultsOverall, 120 patients were identified. The mean age was 49.7 years (range: 5-81); 59.2% were male. Seventy-nine patients (65.8%) had comorbidities, of which cardiovascular diseases was the most common. Most of the abscesses were solitary frontal or temporal lesions. A microbiological diagnosis was secured in 70 (58.3%) of cases, among which the majority were of the Streptococcus spp. Outcome was favorable in 107 (89.2%) of cases. The mortality rate during the initial hospital stay was 2.5%. A total of 10 individuals (8.3%) presented with preoperative delirium or coma, which was associated with an inferior clinical outcome compared to those who exhibited clear consciousness. (p = 0.01).

conclusionsStereotactic aspiration was a safe intervention with a low incidence of complications. The combination of stereotactic aspiration and antibiotic therapy was an effective treatment strategy for brain abscess. Patients who underwent stereotactic aspiration while in a state of disturbance of consciousness demonstrated a poorer outcome compared to those who were conscious. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Brain AbscessStereotaxic TechniquesAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansMaleMiddle AgedRetrospective StudiesSuctionTreatment OutcomeYoung AdultBrain abscessOutcomeStereotactic

Identifiers

PMID40102830
PMCPMC11917069

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