Evidence map›Paper›PMID 40102615›Full record

ArticleEuropean journal of clinical nutrition2025

Influence of body composition on energy metabolism in females with constitutional thinness.

Laurie Isacco, Mélina Bailly, Céline Lambert, Duane Beraud, Martine Duclos, Julien Verney, Yves Boirie, David Thivel

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Article in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laurie IsaccoUniversité Clermont Auvergne, CRNH, AME2P, F-63000, Clermont-Ferrand, France. laurie.isacco@uca.fr.ORCID http://orcid.org/0000-0002-1152-3902
Mélina BaillyUniversité Clermont Auvergne, CRNH, AME2P, F-63000, Clermont-Ferrand, France.
Céline LambertBiostatistics Unit, DRCI, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Duane BeraudUniversité Clermont Auvergne, CRNH, AME2P, F-63000, Clermont-Ferrand, France.
Martine DuclosDepartment of Sport Medicine and Functional Explorations, CHU Clermont-Ferrand, Clermont-Ferrand, France.
Julien VerneyUniversité Clermont Auvergne, CRNH, AME2P, F-63000, Clermont-Ferrand, France.
Yves BoirieUMR 1019, INRA, Clermont-Ferrand, France.ORCID http://orcid.org/0000-0002-3999-1599
David ThivelUniversité Clermont Auvergne, CRNH, AME2P, F-63000, Clermont-Ferrand, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesIndividuals with constitutional thinness are characterized by an atypical resting energy metabolism and body composition. The aim of the present study was to compare patterns of energetic changes from a fasted resting state to i) postprandial resting, ii) fasted exercise, and (iii) postprandial exercise between females with constitutional thinness and normal-weight, considering body weight and composition characteristics. SUBJECTS/

methodsBody composition (X-ray absorptiometry) and maximal aerobic capacities were assessed in 17 female adults with constitutional thinness and 17 normal-weight controls. Their energy expenditure and substrate oxidation were assessed by indirect calorimetry on four occasions: i) in a fasted resting state, ii) two hours after a calibrated meal in a resting state, iii) after a 30-min cycling exercise performed postprandially, and iv) after a 20-min walking exercise in a fasted state.

resultsFemales with constitutional thinness had significantly lower body weight (p < 0.001), absolute fat-free mass (p < 0.001) and percentage of fat mass (p = 0.04). Energy expenditure was lower for all the energetic stimuli considered (from p = 0.02 to p < 0.001) in participants with constitutional thinness compared to normal-weight controls, and differences disappeared after adjustment for body weight or composition.

conclusionsThe present results do not indicate any impaired energetic responses to any energetic stimuli in females with constitutional thinness. Results challenge the hypothesis of a spender energy profile in individuals with constitutional thinness, and highlight the necessity to gain insight into the role of body composition in energetic regulation in this population.

Indexed as

Body CompositionEnergy MetabolismThinnessAbsorptiometry, PhotonAdultBasal MetabolismBody WeightCalorimetry, IndirectExerciseFastingFemaleHumansPostprandial PeriodYoung Adult

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.