Evidence map›Paper›PMID 40102434›Full record

ArticleScientific reports2025

Synthesis, antimicrobial, anti-inflammatory, antioxidant and cytotoxicity of new pyrimidine and pyrimidopyrimidine derivatives.

Reda Mohammed Keshk, Zeinab Ahmed Salama, Samir Kamel Elsaedany, Elsayed Mahmoud Abed ElRehim, Doha Mohammad Beltagy

RetractedAbstract readRetracted Publication
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Innovative Amino-Functionalization of Pyrido[2,3-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Article
  7. Chalcones as Emerging Antibacterial Scaffolds: A Mini Review.Mini reviews in medicinal chemistry · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Reda Mohammed KeshkChemistry Department, Faculty of Science, Damanhour University, Damanhour, 22511, Egypt. redakeshk@sci.dmu.edu.eg.ORCID http://orcid.org/0000-0002-9782-4334
Zeinab Ahmed SalamaChemistry Department, Faculty of Science, Damanhour University, Damanhour, 22511, Egypt.
Samir Kamel ElsaedanyChemistry Department, Faculty of Science, Alexandaria University, Alexandaria, Egypt.
Elsayed Mahmoud Abed ElRehimChemistry Department, Faculty of Science, Damanhour University, Damanhour, 22511, Egypt.
Doha Mohammad BeltagyBiochemistry Department, Faculty of Science, Damanhour University, Damanhour, 22511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel pyrimidine and pyrimidopyrimidine analogs were synthesized in good yield from 6-amino-4-aryl-2-oxo-pyrimidine-5-carbonitrile (1a-d). The synthesized compounds were characterized using various spectral studies, including FT-IR,

Indexed as

Anti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsPyrimidinesCell Line, TumorHumansMCF-7 CellsMicrobial Sensitivity TestsAnti-Infective AgentsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsPyrimidines

Identifiers

PMID40102434
PMCPMC11920053

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.