Evidence map›Paper›PMID 40102310›Full record

ArticleNeuroinformatics2025

Efficient, Automatic, and Reproducible Patch Clamp Data Analysis with "Auto ANT", a User-Friendly Interface for Batch Analysis of Patch Clamp Recordings.

Giusy Pizzirusso, Simon Sundström, Luis Enrique Arroyo-García

Abstract read
In one paragraph

Article in Neuroinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Giusy Pizzirusso *Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 17177, Solna, Sweden. giusy.pizzirusso@ki.se.ORCID http://orcid.org/0000-0001-7704-1239
Simon Sundström *Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 17177, Solna, Sweden.
Luis Enrique Arroyo-GarcíaDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 17177, Solna, Sweden. luis.enrique.arroyogarcia@ki.se.ORCID http://orcid.org/0000-0002-9206-0179

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patch-clamp recordings are vital for investigating the electrical properties of excitable cells, yet the analysis of these recordings often involves time-consuming manual procedures prone to variability. To address this challenge, we developed the Auto ANT (Automated Analysis and Tables) open-source software, an automated, user-friendly graphical interface for the extraction of firing properties and passive membrane properties from patch-clamp recordings. Thanks to the novel built-in automation feature, Auto ANT enables batch analysis of multiple files recorded with the same protocol in minutes. Our tool is designed to streamline data analysis, providing a fast, efficient, and reproducible alternative to manual methods. With a focus on accessibility, Auto ANT allows the users to perform precise comprehensive electrophysiological analyses without requiring programming expertise. By combining automation with a user-centric design, Auto ANT offers a valuable resource for researchers to accelerate data analysis while promoting consistency and reproducibility across different studies.

Indexed as

Data AnalysisPatch-Clamp TechniquesSoftwareUser-Computer InterfaceAction PotentialsAnimalsHumansNeuronsReproducibility of ResultsAction PotentialAnalysisAutomationIntrinsic propertiesPatch-clamp

Identifiers

PMID40102310
PMCPMC11920353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.