ArticleEuropean radiology2025
Early rheumatoid arthritis, two distinctive structural damage patterns revealed by MRI: an 8-year longitudinal study.
Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Median nerve swelling in RA patients: an 8-year longitudinal MRI-based study.Insights into imaging · 2026Article
- Computational approaches to multimodal data integration in rheumatoid arthritis: from data landscape to clinical translation.Briefings in bioinformatics · 2026Review
- Seronegative Rheumatoid Arthritis: A Distinct Immunopathological Entity with Erosive Potential.Medical sciences (Basel, Switzerland) · 2025Review
- Integrating Bibliometrics and Bioinformatics to Map Knowledge Structure and Trend Synthesis in Rheumatoid Arthritis and Bone Erosion (2015-2024).Journal of multidisciplinary healthcare · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo determine how inflammatory and structural parameters change long-term on standard treatment in rheumatoid arthritis patients and which baseline parameter best predicts long-term structural damage. MATERIAL AND
methodsProspective study of early rheumatoid arthritis (ERA) patients (symptom duration ≤ 24 months) who underwent identical clinical, serological, radiographic, and dynamic contrast-enhanced MRI of the wrist assessments at baseline, year-1, and year-8. MR images were analyzed semi-quantitatively (Rheumatoid Arthritis Magnetic Resonance Imaging Score [RAMRIS]) and quantitatively (synovial volume (cm
results81 patients (61 ± 12 years, F/M:67/14) were studied. MRI-detected inflammatory parameters markedly improved from baseline to year-1 and slightly deteriorated from year-1 to year-8 (synovial volume:6.7 ± 5.0→2.6 ± 2.9→3.6 ± 3.3 cm
conclusionIn ERA patients, two distinct structural damage patterns are evident. Baseline bone erosion score is better than clinical, serological, or radiographic assessment at predicting long-term structural damage. KEY POINTS: Questions The value of MRI in predicting long-term structural damage in ERA patients is not clear. Findings This study identified two distinct long-term structural damage progression patterns of ERA patients. MRI can better differentiate between these two groups at baseline than clinical, serological, or radiographic assessment. Clinical relevance MRI examination should be performed in all ERA patients at baseline to determine their structural damage pattern. This will allow a better prediction of patient outcomes in the long-term.
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