Evidence map›Paper›PMID 40101973›Full record

SynthesisBMJ open2025

Association of 15 common dietary factors with tinnitus: a systematic review and meta-analysis of observational studies.

Mengni Zhang, Xiaocui Wang, Shipeng Zhang, Xinyi He, Xi Chen, Lu Wang, Li Fu, Hanyu Wang, Qinwei Fu, Yanjie Jiang and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mengni Zhang *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0001-7437-5209
Xiaocui Wang *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Shipeng Zhang *Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.ORCID http://orcid.org/0000-0002-9462-2841
Xinyi HeHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Xi ChenHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Lu WangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Li FuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Hanyu WangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Qinwei FuHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Yanjie JiangNanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Xinrong LiHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China zhqinxiu@163.com amz.3@163.com.
Qinxiu ZhangHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China zhqinxiu@163.com amz.3@163.com.ORCID http://orcid.org/0000-0001-8746-0277

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA systematic analysis was conducted to investigate the association between tinnitus incidence and daily dietary patterns.

designWe conducted a systematic review and meta-analysis of observational studies. DATA SOURCES: The PubMed, Embase, Web of Science and Cochrane Library databases were searched from their inception to 25 May 2024. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: We included observational studies from peer-reviewed English-language journals that examined tinnitus presence or severity in adults aged 18 years or older, including associated prevalence estimates. DATA EXTRACTION AND SYNTHESIS: Data extraction was independently conducted by two evaluators, who assessed research bias using the Agency for Newcastle-Ottawa Scale and applied evidence classification criteria for aggregate grade strength assessment. This study adhered to the guidelines of the Preferred Reporting Project (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and Meta-Analysis of Epidemiological Observational Studies, as well as the PROSPERO Registry protocols. A mixed-effect model combined maximum adjusted estimates, with heterogeneity measured using the I

resultsA total of 10 retrospective studies were identified and included in this analysis, with the last eight studies incorporated into the meta-analysis. Fifteen dietary factors were examined. Fruit intake, dietary fibre, caffeine and dairy product consumption were negatively correlated with tinnitus incidence (OR=0.649 (95% CI 0.532, 0.793), p<0.0001), (OR=0.918 (95% CI 0.851, 0.990), p=0.03), (OR=0.898 (95% CI 0.862, 0.935), p<0.00001), (OR=0.827 (95% CI 0.766, 0.892), p<0.00001), respectively. A sensitivity analysis confirmed the robustness of the findings.

conclusionsThis systematic review and meta-analysis suggest a link between particular dietary elements and a lower incidence of tinnitus. PROSPERO REGISTRATION NUMBER: CRD42023493856.

Indexed as

DietTinnitusHumansIncidenceObservational Studies as TopicMeta-AnalysisNeurotologyNUTRITION & DIETETICSOTOLARYNGOLOGY

Identifiers

PMID40101973
PMCPMC12010292

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.