Evidence map›Paper›PMID 40101595›Full record

ArticleTicks and tick-borne diseases2025

A new spotted fever group Rickettsia genotype in Haemaphysalis leporispalustris from Maine, USA.

Guang Xu, Elissa Ballman, Nolan Stamborski, Eric L Siegel, Patrick Pearson, Stephen M Rich

Abstract read
In one paragraph

Article in Ticks and tick-borne diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A novelFrontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guang XuDepartment of Microbiology, University of Massachusetts - Amherst, Amherst, MA 01003, USA.
Elissa BallmanSchool of Biology and Ecology, University of Maine, Orono, ME 04469, USA.
Nolan StamborskiDepartment of Microbiology, University of Massachusetts - Amherst, Amherst, MA 01003, USA.
Eric L SiegelDepartment of Microbiology, University of Massachusetts - Amherst, Amherst, MA 01003, USA.
Patrick PearsonDepartment of Microbiology, University of Massachusetts - Amherst, Amherst, MA 01003, USA.
Stephen M RichDepartment of Microbiology, University of Massachusetts - Amherst, Amherst, MA 01003, USA. Electronic address: smrich@umass.edu.

Funding

ACL HHS U01CK000661NCEZID CDC HHS U01 CK000661
6 · The paper itself

Abstract

Spotted fever group (SFG) rickettsioses are increasingly recognized worldwide as threats to public health. Rickettsia rickettsii, Rickettsia parkeri, and Rickettsia rickettsii subspecies californica cause spotted fever rickettsioses, including Rocky Mountain spotted fever. These disease agents are transmitted to humans by various tick vectors in the United States. There is growing concern that other tick species, such as Haemaphysalis leporispalustris, may also transmit new and potentially unrecognized SFG rickettsial pathogens. In this study, we found that 6.1 % of 296 questing H. leporispalustris ticks (21 larvae, 260 nymphs, 9 males, and 6 females) collected from 38 towns across nine counties in Maine, USA, were positive for Rickettsia spp. Further multilocus sequence typing and phylogenetic analysis revealed that this is a new Rickettsia genotype (Rickettsia sp. ME2023) belonging to the SFG group and close to Candidatus Rickettsia lanei. Tick vectors and rickettsial species associated with SFG rickettsioses in New England warrant further investigation. Additionally, the role of H. leporispalustris in pathogen enzootic cycles and transmission requires further study.

Indexed as

Arachnid VectorsGenotypeIxodidaeRickettsiaAnimalsFemaleLarvaMaineMaleMultilocus Sequence TypingNymphPhylogenyGenotypeHaemaphysalis leporispalustrisMaineRickettsiaRickettsia rickettsiiSpotted fever group

Identifiers

PMID40101595
PMCPMC12137007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.