Evidence map›Paper›PMID 40101525›Full record

ArticleDrug and alcohol dependence2025

Daily profiles of nondrug reward and their association with daily outcomes for people in recovery from opioid use disorder: An application of latent profile analysis applied to intensive longitudinal data.

Samuel W Stull, Lisa A Marsch, Stephanie T Lanza

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samuel W StullCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA; Department of Biobehavioral Health, Penn State University, University Park, PA 16802, USA. Electronic address: Samuel.W.Stull@dartmouth.edu.
Lisa A MarschCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA; Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA; Department of Psychiatry, Geisel School of Medicine at Dartmouth, Dartmouth College, Lebanon, NH 03766, USA.
Stephanie T LanzaDepartment of Biobehavioral Health, Penn State University, University Park, PA 16802, USA.

Funding

Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Training in the Science of Co-Occurring DisordersT32DA037202 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2014 to 2026
$4.7M
Promoting Rapid Uptake of Multilevel Latent Class Modeling via Best Practices: Investigating Heterogeneity in Daily Substance Use PatternsR01DA057588 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI STEPHANIE T LANZA · 2023 to 2026
$2.7M
The Role of Nondrug Reward in Recovery from Opioid Use Disorder: Intrapersonal and Socio-spatial Contexts in Daily LifeF31DA057837 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI STULL, SAMUEL · 2023 to 2023
$35k
NIDA NIH HHS F31 DA057837NIDA NIH HHS P30 DA029926NIDA NIH HHS R01 DA057588NIDA NIH HHS T32 DA037202
6 · The paper itself

Abstract

introductionDaily rewarding experiences not involving drugs are complex and may differentially support recovery from addiction. Rarely has nondrug reward, and its multiple facets (i.e. anticipation, meaning etc.), been examined in daily life-this could uncover the acute benefits of different components of nondrug reward on daily recovery outcomes.

methods153 adults in recovery from OUD receiving opioid agonist treatment (M age=41.1, SD=9.5; 57 % women; 84 % white) completed daily diaries for three weeks (2067 person-days), answering 7 continuous items about appraisals of nondrug rewards (e.g., meaning, reward, and anticipation). Item responses were used as indicators in a latent profile analysis. Daily latent profiles of nondrug reward were tested for their association with recovery outcomes (quality of life, mood, craving and use) using robust standard errors to adjust for the multilevel data structure.

resultsThe selected model had four latent profiles (% of days): Highly Anticipated-Rewarding (35 %), Moderately Rewarding (31 %), Minimally Rewarding-Unplanned (22 %), and Highly Rewarding-Unplanned profile (12 %). Relative to the Moderately Rewarding profile, Highly Anticipated-Rewarding was associated with greater positive mood and quality of life and lower negative mood and low-arousal moods. People with more days in the Highly Anticipated-Rewarding Profile (vs. Moderately Rewarding) were less likely to use or crave opioids.

conclusionGreater meaning, reward, and anticipation (including planning) across indicators within profiles were associated with the best recovery outcomes. Latent profile analysis applied to intensive longitudinal data offers an innovative methodological approach for simultaneously assessing multiple daily protective factors that together may differentially promote recovery.

Indexed as

Opioid-Related DisordersRewardAdultAffectCravingFemaleHumansLongitudinal StudiesMaleMiddle AgedOpiate Substitution TreatmentQuality of LifeTreatment OutcomeAddiction recoveryIntensive longitudinal dataLatent profile analysisNondrug rewardOpioid use disorderPositive psychology

Identifiers

PMID40101525
PMCPMC12952496

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.