Evidence map›Paper›PMID 40100591›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2025

Graft-Versus-Host Disease Mouse Models: A Clinical-Translational Perspective.

Jessica Elliott, Rachel Koldej, Amit Khot, David Ritchie

Abstract readReview
PubMed Publisher
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Annals of translational medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica ElliottACRF Translational Research Laboratory, Royal Melbourne Hospital, Melbourne, VIC, Australia. jessica.elliott2@mh.org.au.
Rachel KoldejACRF Translational Research Laboratory, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Amit KhotDepartment of Clinical Haematology, Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
David RitchieACRF Translational Research Laboratory, Royal Melbourne Hospital, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A variety of graft-versus-host disease (GVHD) models have been developed in mice for the purpose of allowing laboratory investigation of the pathobiology, prevention, and treatment of GVHD in humans. While such models are crucial in advancing our knowledge in this field, there are some key limitations that need to be considered when translating laboratory discoveries into the clinical context. This chapter will discuss current clinical practices in transplantation and GVHD and the relative strengths and weaknesses of mouse models that attempt to replicate these states.

Indexed as

Disease Models, AnimalGraft vs Host DiseaseTranslational Research, BiomedicalAnimalsHematopoietic Stem Cell TransplantationHumansMiceAllogeneic stem cell transplantationClinical-translational researchGraft-versus-host diseaseGraft-versus tumor responseMouse modelsTransplantation

Identifiers

PMID40100591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.