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ArticleEsophagus : official journal of the Japan Esophageal Society2025

Current status of prehabilitation before esophagectomy for patients with esophageal cancer among board-certified hospitals by the Japan Esophageal Society.

Tsuyoshi Harada, Tetsuya Tsuji, Takuya Fukushima, Nobuko Konishi, Hiroki Nakajima, Katsuyoshi Suzuki, Tomohiro Ikeda, Shusuke Toyama, Keiji Matsumori, Takumi Yanagisawa and 9 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Esophagus : official journal of the Japan Esophageal Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Tsuyoshi HaradaDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan. tsuyoshi6167@gmail.com.ORCID 0000-0003-4459-8262
Tetsuya TsujiDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Takuya FukushimaFaculty of Rehabilitation, Kansai Medical University, Hirakata, Osaka, Japan.
Nobuko KonishiDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Hiroki NakajimaDepartment of Rehabilitation, Nagoya University Hospital, Nagoya, Aichi, Japan.
Katsuyoshi SuzukiDivision of Rehabilitation Medicine, Shizuoka Cancer Center, Nagaizumi, Shizuoka, Japan.
Tomohiro IkedaDepartment of Rehabilitation Medicine, Okayama University Hospital, Okayama, Okayama, Japan.
Shusuke ToyamaDepartment of Physical Therapy Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan.
Keiji MatsumoriDepartment of Rehabilitation, Shinshu University Hospital, Matsumoto, Nagano, Japan.
Takumi YanagisawaDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Kakeru HashimotoDepartment of Rehabilitation, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Hitoshi KagayaDepartment of Rehabilitation, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan.
Sadamoto ZendaDepartment of Radiation Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
Takashi KojimaDepartment of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
Takeo FujitaDepartment of Esophageal Surgery, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.
Junya UenoDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Nanako HijikataDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Aiko IshikawaDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.
Ryuichi HayashiDepartment of Rehabilitation Medicine, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrehabilitation has been shown to prevent postoperative pneumonia and physical function decline after esophagectomy in recent systematic reviews and meta-analyses. However, the implementation status of prehabilitation for esophagectomy remains unknown. This nationwide survey was performed to investigate the current status of and barriers to prehabilitation before esophagectomy among Japanese hospitals.

methodsThis multicenter nationwide survey was performed using the postal mail method. The eligible facilities were 155 Japanese hospitals that had been certified as Authorized Institutes for Board-Certified Esophageal Surgeons by the Japan Esophageal Society within the past 10 years. We administered the original questionnaire to investigate the current status of prehabilitation before esophagectomy, excluding neoadjuvant therapy.

resultsThe response rate was 75% (117/155 facilities). The number of facilities providing prehabilitation for esophagectomy was 77 (66%), including prehabilitation in the preoperative outpatient setting in 39 (33%) and in the preoperative inpatient setting in 53 (45%). Among the facilities that did not provide prehabilitation, the most common reasons for not providing prehabilitation (i.e., responses of "agree" and "strongly agree" on questionnaire) were a lack of human resources, preoperative period too short to provide prehabilitation, difficultly using reimbursed medical fees, and no establishment of a standard prehabilitation program.

conclusionsWe elucidated the current implementation status of prehabilitation, identified the critical gap between evidence and practice. This information will contribute to building an effective medical system and framework of prehabilitation for patients with esophageal cancer in Japan and other countries.

Indexed as

Esophageal NeoplasmsEsophagectomyPostoperative ComplicationsPreoperative CarePreoperative ExerciseHospitalsHumansJapanSocieties, MedicalSurveys and QuestionnairesEsophagectomyImplementation statusNationwide surveyPrehabilitation

Identifiers

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.