Evidence map›Paper›PMID 40100427›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Physical activity, health-related fitness, and physical performance in children with acquired hypothalamic dysfunction.

I M A A Van Roessel, J Van Schaik, L B Kleinlugtenbelt, S N van Duijn, M Burghard, T Takken, W J E Tissing, W P Bekkering, H M van Santen

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

I M A A Van Roessel *Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, The Netherlands. i.m.a.vanroessel@umcutrecht.nl.
J Van Schaik *Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, The Netherlands.
L B Kleinlugtenbelt *Division of Pediatric Neuro-Oncology, Department of Supportive Care, Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
S N van DuijnDivision of Pediatric Neuro-Oncology, Department of Supportive Care, Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
M BurghardDepartment of Exercise Physiology, Child Development & Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, The Netherlands.
T TakkenDepartment of Exercise Physiology, Child Development & Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, The Netherlands.
W J E TissingDivision of Pediatric Neuro-Oncology, Department of Supportive Care, Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
W P BekkeringDepartment of Exercise Physiology, Exercise Center, Princess Máxima Center for Pediatric Oncology, University Medical Center Utrecht, Heidelberglaan 25, 3584 CS, Utrecht, The Netherlands.
H M van SantenDepartment of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Lundlaan 6, 3584 EA, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurvivors of a pediatric suprasellar tumor may suffer from hypothalamic-pituitary dysfunction (HD), which may result in hypothalamic obesity (HO). The first step in HO treatment is lifestyle intervention (e.g. exercise). Our aim was to assess physical activity (PA), health-related fitness (HRF) and physical performance (PP) in a cohort of children with a suprasellar tumor.

methodsRetrospective study on a national cohort including all children with a suprasellar tumor who were referred to the physiotherapy department 2018-2022. Data was collected on: PA defined as minutes of Moderate-to-Vigorous Physical Activity (MVPA) and number of steps per day, HRF defined as body composition, VO

resultsSeventy-three children (mean age 11.09, mean body mass index SDS 2.36) were evaluated. In total, 24.1% reached the guideline of ≥ 60 min MVPA per day. The VO

Indexed as

ExerciseHypothalamic DiseasesPhysical FitnessPhysical Functional PerformanceAdolescentChildFemaleHumansMaleMuscle StrengthRetrospective StudiesCardiorespiratory fitnessChildhood brain tumor survivorsHypothalamic-pituitary dysfunctionLifestylePhysiotherapy

Identifiers

PMID40100427
PMCPMC11920002

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.