Evidence map›Paper›PMID 40100414›Full record

ArticleLung2025

Effect of Electronic Cigarette Vapour Exposure on Ca

Ya Niu, Chung-Yin Yip, Ke-Wu Pan, Judith Choi-Wo Mak, Wing-Hung Ko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ya NiuSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Chung-Yin YipSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Ke-Wu PanSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.
Judith Choi-Wo MakDepartment of Pharmacology & Pharmacy, The University of Hong Kong, Hong Kong, China.
Wing-Hung KoSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. whko@cuhk.edu.hk.ORCID http://orcid.org/0000-0002-2041-402X

Funding

Health and Medical Research Fund, the Food and Health Bureau, and the Government of the Hong Kong Special Administrative Region 07183806Research Grant Council General Research Fund CUHK 14107920
6 · The paper itself

Abstract

purposeThe popularity of electronic cigarettes (e-cigarettes) has grown exponentially over the past few years, and teenagers now prefer them to tobacco cigarettes. We determined whether exposure to e-cigarette vapour (e-vapour) adversely affects ion transport using human airway epithelial cell lines 16HBE14o- and Calu-3 and well-differentiated primary human bronchial epithelial cells (HBEs).

methodsWe concurrently measured fluorescent signals and short-circuit current (I

resultsWe compared the effects of e-vapour to those of traditional cigarette smoke (CS) on the human airway cell models. In all three cell types, e-vapour, similar to CS, significantly reduced agonist-induced increases in Ca

conclusionOur data suggest that e-vapour is not harmless and causes ion transport dysfunction similar to CS, thereby predisposing e-cigarette users to vaping-induced lung injury.

Indexed as

BronchiCalciumCyclic AMPE-Cigarette VaporElectronic Nicotine Delivery SystemsEpithelial CellsRespiratory MucosaCell LineHumansIon TransportSignal TransductionSmokeCalciumCyclic AMPE-Cigarette VaporSmokeAirway epitheliaCa2+cAMPCFTRE-cigaretteIon transport

Identifiers

PMID40100414
PMCPMC11920333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.