Evidence map›Paper›PMID 40100336›Full record

ArticleCanadian journal of public health = Revue canadienne de sante publique2025

The evolving HIV epidemic in Ontario, Canada: A retrospective analysis of new HIV diagnoses to identify subpopulations with persistent risk of HIV transmission.

Abigail Kroch, David Gogolishvili, Kristen O'Brien, Lauren Orser, Kevin Woodward, Wangari Tharao, Daniel Lazzam, Katherine Burress, Majorie Kabahenda, Mona Loutfy and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Canadian journal of public health = Revue canadienne de sante publique, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abigail KrochOntario HIV Treatment Network, Toronto, ON, Canada. aekroch@gmail.com.ORCID 0000-0002-9137-2461
David GogolishviliOntario HIV Treatment Network, Toronto, ON, Canada.
Kristen O'BrienOntario HIV Treatment Network, Toronto, ON, Canada.
Lauren OrserUniversity of Ottawa School of Nursing, Ottawa, ON, Canada.
Kevin WoodwardDivision of Infectious Diseases at McMaster University, Hamilton, ON, Canada.
Wangari TharaoWomen's Health in Women's Hands, Toronto, ON, Canada.
Daniel LazzamDepartment of Medicine, McMaster University, Hamilton, ON, Canada.
Katherine BurressMaple Leaf Medical Clinic, Toronto, ON, Canada.
Majorie KabahendaWomen's Health in Women's Hands, Toronto, ON, Canada.
Mona LoutfyMaple Leaf Medical Clinic, Toronto, ON, Canada.
Patrick O'ByrneUniversity of Ottawa School of Nursing, Ottawa, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study was to characterize new HIV diagnoses in key Ontario cities, in order to understand current drivers of continued HIV transmission to inform HIV testing and prevention efforts.

methodsChart reviews were carried out at four clinical sites in Ontario, Canada. The study population included individuals who were diagnosed with HIV in Ottawa, Hamilton, and Toronto between January 1, 2018, and December 31, 2020, and had no previous evidence of HIV documented.

resultsThe total number of persons in this analysis was 359, from Toronto (n = 201), Ottawa (n = 88), and Hamilton (n = 70). More than half of the diagnoses were among those who immigrated to Canada, and many were diagnosed (11%) during the year they arrived. Many participants experienced a late diagnosis (43.2%), and while 116 (32.3%) had HIV testing history in Ontario, 155 did not (43.2%). Many participants were men who have sex with men (MSM) and had a previously recorded diagnosis of gonorrhea or chlamydia (n = 27; 7.5%) or syphilis (n = 39; 10.9%). Among women and heterosexual men, a diagnosis of hepatitis C (n = 18; 5.0%) appeared to signal a risk of HIV diagnosis.

conclusionThese data show that HIV testing and prevention strategies should be targeted to (1) MSM with a history of syphilis, gonorrhea, or chlamydia; (2) heterosexual men and women with a history of hepatitis C; and (3) immigrants within the first 5 years of migration. To address the evolving epidemic, it will be necessary to employ targeted HIV screening and prevention measures.

Indexed as

AIDS SerodiagnosisEmigrants and ImmigrantsHIV InfectionsAdultChlamydia InfectionsEpidemicsFemaleGonorrheaHepatitis CHuman MigrationHumansMaleMiddle AgedOntarioRetrospective StudiesRisk FactorsGay men’s healthHIVHIV epidemiologyImmigration healthSurveillance

Identifiers

PMID40100336
PMCPMC12753610

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.