ArticleAbdominal radiology (New York)2025
Predicting variant histology in bladder cancer: the role of multiparametric MRI and vesical imaging-reporting and data system (VI-RADS).
Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A Novel Model for Muscle-Invasive Bladder Cancer Diagnosis Using Contrast-Enhanced Ultrasound.Annals of surgical oncology · 2026Article
- Article
- [Innovative imaging techniques for urothelial carcinoma].Urologie (Heidelberg, Germany) · 2026Review
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5 authors.
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Abstract
objectives(1) To evaluate the diagnostic performance of the VI-RADS score in detecting muscle invasion in variant urothelial carcinomas (VUC). (2) To identify spesific MRI features that may serve as predicting for VUC.
methodsTwo hundred four patients who underwent TUR-B and/or radical cystectomy and a bladder mpMRI scan within three months prior to the procedure were retrospectively enrolled. The tumors were divided into two histological cohorts: pure urothelial carcinoma (PUC) and VUC. Various MRI features, including largest tumor diameter, long-to-short axis ratio, morphology, heterogeneous signal intensity (SI), presence of necrosis, and normalized ADC (ADC
resultsOur study identified several MRI features significantly associated with VUC, including heterogeneous SI on T2-weighted images (OR: 3.055; 95% CI: 1.312-7.112; p < 0.001), dynamic contrast enhancement images (OR: 2.935; 95% CI: 1.263-6.821; p < 0.001), and the presence of necrosis (OR: 3.575; 95% CI: 1.798-7.107; p < 0.001). Additionally, ADC
conclusionVI-RADS score can be used with high performance to detect muscle invasion in VUC, regardless of reader experience. Additionally, specific MRI features such as heterogeneous SI, the presence of necrosis, and ADC
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