Evidence map›Paper›PMID 40100075›Full record

ArticleJournal of the American Chemical Society2025

Diversity Synthesis Using Glutarimides as Rhodium Carbene Precursors in Enantioselective C-H Functionalization and Cyclopropanation.

William F Tracy, Jack C Sharland, Duc Ly, Geraint H M Davies, Djamaladdin G Musaev, Hua Fang, Jesus Moreno, Emily C Cherney, Huw M L Davies

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Asymmetric C-H Functionalization ofJournal of the American Chemical Society · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

William F TracyDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0003-1157-7684
Jack C SharlandDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Duc LyDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0002-0829-5080
Geraint H M DaviesDiscovery and Development Sciences, Bristol Myers Squibb, Cambridge, Massachusetts 02143, United States.ORCID 0000-0002-5986-0756
Djamaladdin G MusaevDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0003-1160-6131
Hua FangDiscovery and Development Sciences, Bristol Myers Squibb, Princeton, New Jersey 08543, United States.
Jesus MorenoDiscovery and Development Sciences, Bristol Myers Squibb, San Diego, California 92121, United States.ORCID 0009-0001-2671-2386
Emily C CherneyDiscovery and Development Sciences, Bristol Myers Squibb, Princeton, New Jersey 08543, United States.
Huw M L DaviesDepartment of Chemistry, Emory University, Atlanta, Georgia 30322, United States.ORCID 0000-0001-6254-9398

Funding

N-Sulfonyltriazoles as Carbene PrecursorsR01GM099142 · NIGMS · EMORY UNIVERSITY · PI DAVIES, HUW M · 2011 to 2023
$4.1M
NIGMS NIH HHS R01 GM099142
6 · The paper itself

Abstract

Cereblon E3 ligase modulatory drugs (CELMoDs) can be used to target proteins and mark them for proteasomal degradation by recruiting them to cereblon (CRBN), the substrate receptor of the CRL4

Indexed as

CyclopropanesMethanePiperidonesRhodiumCatalysisMolecular StructureStereoisomerismcarbeneCyclopropanesglutarimideMethanePiperidonesRhodium

Identifiers

PMID40100075
PMCPMC11969559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.